Verit Fatma Ferda, Kucukakca Ayse Seyma Ozsuer
Department of Obstetrics and Gynecology, University of Health Sciences, Istanbul Training and Research Hospital, Istanbul, Turkey.
Department of Obstetrics and Gynecology, Bezmialem Foundation University, Istanbul, Turkey.
Clin Exp Reprod Med. 2021 Mar;48(1):80-84. doi: 10.5653/cerm.2020.03776. Epub 2021 Feb 18.
The aim of the study was to investigate pregnancy, obstetric, and neonatal outcomes in women with small (<4 cm) unilateral endometriomas.
This retrospective study included 177 patients: 91 patients with small endometriomas and 86 controls with unexplained or tubal factor infertility who were treated at the Süleymaniye Gynecology and Maternity Training and Research Hospital Infertility Unit between January 2010 and July 2015. The groups were matched with regards to demographic characteristics such as age, body mass index, and infertility duration. All of the women in this study conceived via intracytoplasmic sperm injection. We compared pregnancy, obstetric, and neonatal outcomes between these groups.
Women with endometriomas had a higher biochemical pregnancy rate, but lower clinical pregnancy and live birth rates than women with unexplained and tubal factor infertility (p<0.05 for all). However no significant differences were found in terms of obstetric and neonatal complications between the two groups (p>0.05 for all).
In this study, we found that women with endometriomas less than 4 cm were more prone to early pregnancy complications. We also showed that this group did not have any increased risks of late pregnancy, obstetric, and neonatal complications.
本研究旨在调查单侧小（<4 cm）子宫内膜异位症患者的妊娠、产科及新生儿结局。
这项回顾性研究纳入了177例患者：91例患有小子宫内膜异位症的患者以及86例不明原因或输卵管因素导致不孕的对照者，这些患者于2010年1月至2015年7月在苏莱曼尼耶妇产科培训与研究医院不孕不育科接受治疗。两组在年龄、体重指数和不孕持续时间等人口统计学特征方面进行了匹配。本研究中的所有女性均通过卵胞浆内单精子注射受孕。我们比较了两组之间的妊娠、产科及新生儿结局。
与不明原因及输卵管因素导致不孕的女性相比，患有子宫内膜异位症的女性生化妊娠率较高，但临床妊娠率和活产率较低（所有p<0.05）。然而，两组在产科及新生儿并发症方面未发现显著差异（所有p>0.05）。
在本研究中，我们发现小于4 cm的子宫内膜异位症女性更容易出现早期妊娠并发症。我们还表明，该组在晚期妊娠、产科及新生儿并发症方面没有任何增加的风险。
