State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.
Queen Mary School, Jiangxi Medical College, Nanchang University, Nanchang 330006, China.
Food Res Int. 2021 Feb;140:109858. doi: 10.1016/j.foodres.2020.109858. Epub 2020 Nov 2.
As a complex ecosystem of the human body, the intestinal flora maintains a dynamic balance with the host and plays an irreplaceable role in life activities such as nutritional metabolism and host immunity. The intestinal flora interacts with polysaccharides, the intestinal flora digests non-digestible polysaccharides, and polysaccharides can be used as an important energy source for intestinal microorganisms. Disturbance of the gut microbiota (GM) leads to the occurrence of diseases, polysaccharides as prebiotics can improve the disease by regulating the composition of GM. In this paper, we reviewed the current knowledge about the relationship between polysaccharides, gut microbiota, and and human health, described the microbial composition of the human, the relationship between intestinal flora disorders and disease occurrence, and summarized the interactions between polysaccharides and intestinal microorganisms.
作为人体的一个复杂生态系统，肠道菌群与宿主保持着动态平衡，在营养代谢和宿主免疫等生命活动中发挥着不可替代的作用。肠道菌群与多糖相互作用，肠道菌群消化不可消化的多糖，而多糖可以作为肠道微生物的重要能量来源。肠道微生物群（GM）的紊乱会导致疾病的发生，多糖作为益生元可以通过调节 GM 的组成来改善疾病。本文综述了多糖、肠道菌群与人体健康之间关系的最新知识，描述了人体的微生物组成、肠道菌群紊乱与疾病发生的关系，并总结了多糖与肠道微生物之间的相互作用。
