Wang Hui, Sun Zhuoran, Wang Longjie, Zou Da, Li Weishi
Orthopaedic Department of Peking University Third Hospital, Beijing, China.
Beijing Key Laboratory of Spinal Disease Research, Beijing, China.
Global Spine J. 2023 Jan;13(1):149-155. doi: 10.1177/2192568221994082. Epub 2021 Mar 2.
Retrospective radiological analysis.
To explore whether proximal fusion level above first coronal reverse vertebrae (FCRV) could decrease risk of adjacent segment degeneration (ASD) in degenerative lumbar scoliosis (DLS).
One hundred and 16 DLS patients were divided into 2 groups according to occurrence of ASD: study group (ASD positive group) and control group (ASD negative group). FCRV was defined as the first vertebrae that presents opposite orientation of asymmetric Hounsfield unit (HU) ratio from the other vertebrae within major curve. Incidence of ASD was evaluated in subgroups according to location between FCRV and upper instrumented vertebrae (UIV).
The fusion level was shorter in study group than that in control group. There were 12 patients presented FCRV 2-level proximal than SV, 32 patients presented FCRV 1-level proximal than SV, 35 patients presented the same vertebra of FCRV with SV, 23 patients presented FCRV 1-level distal than SV, 14 patients presented FCRV 2-level distal than SV. When UIV located above FCRV, no patient presented ASD, while 15.4% patients presented ASD when UIV located on FCRV. In study group, proximal scoliosis progression was detected in 1 patient (3.9%) when UIV located on FCRV, and 17 patients (29.8%) when UIV located below FCRV.
Proximal fusion level above FCRV could decrease the risk of ASD in DLS, especially for the proximal scoliosis progression. FCRV represent the transitional point of the mechanical load on coronal plane, and may be within a more stable condition than stable vertebrae measured from radiographs.
回顾性放射学分析。
探讨在退行性腰椎侧凸(DLS)中,第一冠状位反向椎体(FCRV)上方的近端融合水平是否能降低相邻节段退变(ASD)的风险。
116例DLS患者根据是否发生ASD分为两组:研究组(ASD阳性组)和对照组(ASD阴性组)。FCRV定义为在主弯内与其他椎体相比呈现不对称Hounsfield单位(HU)比值相反方向的第一个椎体。根据FCRV与上位固定椎体(UIV)之间的位置,在亚组中评估ASD的发生率。
研究组的融合节段比对照组短。有12例患者的FCRV比骶骨顶点(SV)高2个节段,32例患者的FCRV比SV高1个节段,35例患者的FCRV与SV为同一椎体,23例患者的FCRV比SV低1个节段,14例患者的FCRV比SV低2个节段。当UIV位于FCRV上方时,无患者发生ASD,而当UIV位于FCRV时,15.4%的患者发生ASD。在研究组中,当UIV位于FCRV时,1例患者(3.9%)出现近端脊柱侧凸进展,当UIV位于FCRV下方时,17例患者(29.8%)出现近端脊柱侧凸进展。
FCRV上方的近端融合水平可降低DLS中ASD的风险,尤其是对于近端脊柱侧凸进展。FCRV代表冠状面上机械负荷的过渡点,并且可能比X线片测量的稳定椎体处于更稳定的状态。