• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

第一冠状反向椎体上方的近端融合节段:降低退变性腰椎侧凸相邻节段退变风险的关键因素

Proximal Fusion Level Above First Coronal Reverse Vertebrae: An Essential Factor Decreasing the Risk of Adjacent Segment Degeneration in Degenerative Lumbar Scoliosis.

作者信息

Wang Hui, Sun Zhuoran, Wang Longjie, Zou Da, Li Weishi

机构信息

Orthopaedic Department of Peking University Third Hospital, Beijing, China.

Beijing Key Laboratory of Spinal Disease Research, Beijing, China.

出版信息

Global Spine J. 2023 Jan;13(1):149-155. doi: 10.1177/2192568221994082. Epub 2021 Mar 2.

DOI:10.1177/2192568221994082
PMID:33648368
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9837505/
Abstract

STUDY DESIGN

Retrospective radiological analysis.

OBJECTIVE

To explore whether proximal fusion level above first coronal reverse vertebrae (FCRV) could decrease risk of adjacent segment degeneration (ASD) in degenerative lumbar scoliosis (DLS).

METHODS

One hundred and 16 DLS patients were divided into 2 groups according to occurrence of ASD: study group (ASD positive group) and control group (ASD negative group). FCRV was defined as the first vertebrae that presents opposite orientation of asymmetric Hounsfield unit (HU) ratio from the other vertebrae within major curve. Incidence of ASD was evaluated in subgroups according to location between FCRV and upper instrumented vertebrae (UIV).

RESULTS

The fusion level was shorter in study group than that in control group. There were 12 patients presented FCRV 2-level proximal than SV, 32 patients presented FCRV 1-level proximal than SV, 35 patients presented the same vertebra of FCRV with SV, 23 patients presented FCRV 1-level distal than SV, 14 patients presented FCRV 2-level distal than SV. When UIV located above FCRV, no patient presented ASD, while 15.4% patients presented ASD when UIV located on FCRV. In study group, proximal scoliosis progression was detected in 1 patient (3.9%) when UIV located on FCRV, and 17 patients (29.8%) when UIV located below FCRV.

CONCLUSIONS

Proximal fusion level above FCRV could decrease the risk of ASD in DLS, especially for the proximal scoliosis progression. FCRV represent the transitional point of the mechanical load on coronal plane, and may be within a more stable condition than stable vertebrae measured from radiographs.

摘要

研究设计

回顾性放射学分析。

目的

探讨在退行性腰椎侧凸(DLS)中,第一冠状位反向椎体(FCRV)上方的近端融合水平是否能降低相邻节段退变(ASD)的风险。

方法

116例DLS患者根据是否发生ASD分为两组:研究组(ASD阳性组)和对照组(ASD阴性组)。FCRV定义为在主弯内与其他椎体相比呈现不对称Hounsfield单位(HU)比值相反方向的第一个椎体。根据FCRV与上位固定椎体(UIV)之间的位置,在亚组中评估ASD的发生率。

结果

研究组的融合节段比对照组短。有12例患者的FCRV比骶骨顶点(SV)高2个节段,32例患者的FCRV比SV高1个节段,35例患者的FCRV与SV为同一椎体,23例患者的FCRV比SV低1个节段,14例患者的FCRV比SV低2个节段。当UIV位于FCRV上方时,无患者发生ASD,而当UIV位于FCRV时,15.4%的患者发生ASD。在研究组中,当UIV位于FCRV时,1例患者(3.9%)出现近端脊柱侧凸进展,当UIV位于FCRV下方时,17例患者(29.8%)出现近端脊柱侧凸进展。

结论

FCRV上方的近端融合水平可降低DLS中ASD的风险,尤其是对于近端脊柱侧凸进展。FCRV代表冠状面上机械负荷的过渡点,并且可能比X线片测量的稳定椎体处于更稳定的状态。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59b2/9837505/ee18e4883ecf/10.1177_2192568221994082-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59b2/9837505/ad1067cd244d/10.1177_2192568221994082-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59b2/9837505/499eef759f9d/10.1177_2192568221994082-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59b2/9837505/e0622e28b59a/10.1177_2192568221994082-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59b2/9837505/21b61dda930d/10.1177_2192568221994082-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59b2/9837505/ee18e4883ecf/10.1177_2192568221994082-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59b2/9837505/ad1067cd244d/10.1177_2192568221994082-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59b2/9837505/499eef759f9d/10.1177_2192568221994082-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59b2/9837505/e0622e28b59a/10.1177_2192568221994082-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59b2/9837505/21b61dda930d/10.1177_2192568221994082-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59b2/9837505/ee18e4883ecf/10.1177_2192568221994082-fig5.jpg

相似文献

1
Proximal Fusion Level Above First Coronal Reverse Vertebrae: An Essential Factor Decreasing the Risk of Adjacent Segment Degeneration in Degenerative Lumbar Scoliosis.第一冠状反向椎体上方的近端融合节段:降低退变性腰椎侧凸相邻节段退变风险的关键因素
Global Spine J. 2023 Jan;13(1):149-155. doi: 10.1177/2192568221994082. Epub 2021 Mar 2.
2
Upper instrumented vertebrae selection criteria for degenerative lumbar scoliosis based on the hounsfield unit asymmetry of the first coronal reverse vertebrae: an observational study.基于第一冠状位反曲椎体的 Hounsfield 单位不对称性选择退行性腰椎侧凸的上位固定椎的标准:一项观察性研究。
J Orthop Surg Res. 2023 Nov 1;18(1):819. doi: 10.1186/s13018-023-04325-z.
3
Selection of proximal fusion level for adult degenerative lumbar scoliosis.成人退变性腰椎侧凸的近侧融合节段选择。
Eur Spine J. 2013 Feb;22(2):394-401. doi: 10.1007/s00586-012-2527-1. Epub 2012 Oct 14.
4
Reliability of end, stable, neutral, first coronal reverse vertebrae identification in degenerative lumbar scoliosis: Intra- and interobserver consistency analysis.退行性腰椎侧凸中终末、稳定、中立、首节冠状面反向椎体识别的可靠性:观察者内和观察者间一致性分析。
Front Surg. 2023 Feb 13;10:1116590. doi: 10.3389/fsurg.2023.1116590. eCollection 2023.
5
[Clinical effects of different methods of the proximal fusion for long segmental lumbar vertebrae fusion in treatment of degenerative lumbar scoliosis].[不同近端融合方法用于长节段腰椎融合治疗退变性腰椎侧凸的临床疗效]
Zhonghua Yi Xue Za Zhi. 2016 Dec 6;96(45):3674-3679. doi: 10.3760/cma.j.issn.0376-2491.2016.45.014.
6
The association between lower Hounsfield units of the upper instrumented vertebra and proximal junctional kyphosis in adult spinal deformity surgery with a minimum 2-year follow-up.在至少2年随访的成人脊柱畸形手术中,上位固定椎体较低的亨氏单位与近端交界性后凸之间的关联。
Neurosurg Focus. 2020 Aug;49(2):E7. doi: 10.3171/2020.5.FOCUS20192.
7
Hounsfield Unit for Assessing Vertebral Bone Quality and Asymmetrical Vertebral Degeneration in Degenerative Lumbar Scoliosis.评估退行性腰椎侧凸中脊柱骨质量和不对称性脊柱退变的 Hounsfield 单位。
Spine (Phila Pa 1976). 2020 Nov 15;45(22):1559-1566. doi: 10.1097/BRS.0000000000003639.
8
Hyper-Selective Posterior Fusion in Lenke 5C Adolescent Idiopathic Scoliosis: When Can We Stop Below the Upper End Vertebra?后路超选择性融合治疗 Lenke 5C 型青少年特发性脊柱侧凸:我们可以在顶椎下方多融合几节椎体?
Spine (Phila Pa 1976). 2020 Sep 15;45(18):1269-1276. doi: 10.1097/BRS.0000000000003513.
9
Prophylactic vertebral cement augmentation at the uppermost instrumented vertebra and rostral adjacent vertebra for the prevention of proximal junctional kyphosis and failure following long-segment fusion for adult spinal deformity.预防性椎体骨水泥强化术用于成人脊柱畸形长节段融合术后最上端固定椎体及相邻头侧椎体,以预防近端交界性后凸和失败。
Spine J. 2017 Oct;17(10):1499-1505. doi: 10.1016/j.spinee.2017.05.015. Epub 2017 May 15.
10
Preoperative Risk Factors for Adjacent Segment Degeneration after Two-Level Floating Posterior Fusion at L3-L5.L3-L5 节段二级浮动后路融合术后相邻节段退变的术前危险因素
Spine Surg Relat Res. 2019 Apr 26;4(1):43-49. doi: 10.22603/ssrr.2019-0003. eCollection 2020.

引用本文的文献

1
The Safety and Effectiveness of Multi-Segment Cortical Bone Trajectory Screws in Adult Degenerative Scoliosis with Stenosis Among the Elderly: Minimum 5-year Follow-up Study.多节段皮质骨轨迹螺钉在老年成人退变性脊柱侧凸伴狭窄中的安全性和有效性:至少5年随访研究
Clin Interv Aging. 2025 Jul 28;20:1125-1135. doi: 10.2147/CIA.S527306. eCollection 2025.
2
Hounsfield unit correlates with intervertebral disc degeneration in premenopausal and menopausal women: a radiological study.Hounsfield单位与绝经前和绝经后女性的椎间盘退变相关:一项影像学研究。
J Orthop Surg Res. 2025 Apr 9;20(1):356. doi: 10.1186/s13018-025-05770-8.
3

本文引用的文献

1
Hounsfield Unit for Assessing Vertebral Bone Quality and Asymmetrical Vertebral Degeneration in Degenerative Lumbar Scoliosis.评估退行性腰椎侧凸中脊柱骨质量和不对称性脊柱退变的 Hounsfield 单位。
Spine (Phila Pa 1976). 2020 Nov 15;45(22):1559-1566. doi: 10.1097/BRS.0000000000003639.
2
Outcomes of Short Fusion versus Long Fusion for Adult Degenerative Scoliosis: A Systematic Review and Meta-analysis.成人退行性脊柱侧凸短节段融合与长节段融合的疗效:一项系统评价和荟萃分析。
Orthop Surg. 2017 Nov;9(4):342-349. doi: 10.1111/os.12357.
3
Incidence and risk factors for the progression of proximal junctional kyphosis in degenerative lumbar scoliosis following long instrumented posterior spinal fusion.
Biomechanical Characteristics of First Coronal Reverse Vertebrae in Lenke Type V Adolescent Idiopathic Scoliosis: A Study Using Finite Element Analysis.
Lenke V型青少年特发性脊柱侧凸中首例冠状位反向椎体的生物力学特征:一项有限元分析研究
Orthop Surg. 2025 Feb;17(2):563-574. doi: 10.1111/os.14294. Epub 2024 Dec 9.
4
Hounsfield units and vertebral bone quality score for predicting mechanical complications after adult spinal deformity surgery: a systematic review and meta-analysis.用于预测成人脊柱畸形手术后机械性并发症的亨氏单位和椎体骨质量评分:一项系统评价和荟萃分析
Asian Spine J. 2024 Oct;18(5):719-730. doi: 10.31616/asj.2023.0402. Epub 2024 Oct 22.
5
Upper instrumented vertebrae selection criteria for degenerative lumbar scoliosis based on the hounsfield unit asymmetry of the first coronal reverse vertebrae: an observational study.基于第一冠状位反曲椎体的 Hounsfield 单位不对称性选择退行性腰椎侧凸的上位固定椎的标准:一项观察性研究。
J Orthop Surg Res. 2023 Nov 1;18(1):819. doi: 10.1186/s13018-023-04325-z.
6
Reliability of end, stable, neutral, first coronal reverse vertebrae identification in degenerative lumbar scoliosis: Intra- and interobserver consistency analysis.退行性腰椎侧凸中终末、稳定、中立、首节冠状面反向椎体识别的可靠性:观察者内和观察者间一致性分析。
Front Surg. 2023 Feb 13;10:1116590. doi: 10.3389/fsurg.2023.1116590. eCollection 2023.
7
Hounsfield Unit for Assessing Bone Mineral Density Distribution Within Cervical Vertebrae and Its Correlation With the Intervertebral Disc Degeneration.评估颈椎骨矿物质密度分布的亨氏单位及其与椎间盘退变的相关性。
Front Endocrinol (Lausanne). 2022 Jul 8;13:920167. doi: 10.3389/fendo.2022.920167. eCollection 2022.
8
Bone Density Distribution in the Cervical Spine.颈椎骨密度分布
Global Spine J. 2024 Jan;14(1):169-176. doi: 10.1177/21925682221098965. Epub 2022 Apr 29.
长节段后路器械脊柱融合术后退行性腰椎侧凸近端交界性后凸进展的发生率及危险因素
Medicine (Baltimore). 2016 Aug;95(32):e4443. doi: 10.1097/MD.0000000000004443.
4
Diagnostic efficacy of Hounsfield units in spine CT for the assessment of real bone mineral density of degenerative spine: correlation study between T-scores determined by DEXA scan and Hounsfield units from CT.亨氏单位在脊柱CT中对评估退变脊柱真实骨密度的诊断效能:双能X线吸收法扫描测定的T值与CT亨氏单位之间的相关性研究
Acta Neurochir (Wien). 2016 Jul;158(7):1421-7. doi: 10.1007/s00701-016-2821-5. Epub 2016 May 13.
5
Trabecular bone of precocials at birth; Are they prepared to run for the wolf(f)?早成雏出生时的小梁骨;它们准备好躲避危险了吗? (注:原句中“run for the wolf(f)”表述可能有误,推测是“run for the wolf”,直译为“为狼奔跑”,意译为“躲避狼(代表危险等)” ,这里按推测意译给出译文,具体可根据更准确的原文进一步调整 )
J Morphol. 2016 Jul;277(7):948-56. doi: 10.1002/jmor.20548. Epub 2016 Apr 20.
6
Predisposing Characteristics of Adjacent Segment Disease After Lumbar Fusion.腰椎融合术后相邻节段疾病的易患特征。
Spine (Phila Pa 1976). 2016 Jul 15;41(14):1167-1172. doi: 10.1097/BRS.0000000000001493.
7
Progression of Coronal Cobb Angle After Short-Segment Lumbar Interbody Fusion in Patients with Degenerative Lumbar Stenosis.退行性腰椎管狭窄症患者短节段腰椎椎间融合术后冠状面Cobb角的进展
World Neurosurg. 2016 May;89:510-6. doi: 10.1016/j.wneu.2016.01.051. Epub 2016 Feb 2.
8
Wolff's law in action: a mechanism for early knee osteoarthritis.沃尔夫定律的作用:早期膝关节骨关节炎的一种机制
Arthritis Res Ther. 2015 Sep 1;17(1):207. doi: 10.1186/s13075-015-0738-7.
9
Selection of proximal fusion level for degenerative scoliosis and the entailing proximal-related late complications.退行性脊柱侧凸近端融合节段的选择及其相关的近端晚期并发症。
Int J Clin Exp Med. 2015 Apr 15;8(4):5731-8. eCollection 2015.
10
The importance of proximal fusion level selection for outcomes of multi-level lumbar posterolateral fusion.近端融合节段选择对多节段腰椎后外侧融合术疗效的重要性。
Clin Orthop Surg. 2015 Mar;7(1):77-84. doi: 10.4055/cios.2015.7.1.77. Epub 2015 Feb 10.