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导电聚合物在减少新冠肺炎患者继发性细菌感染中的潜在应用:综述

Potential Applications of Conducting Polymers to Reduce Secondary Bacterial Infections among COVID-19 Patients: a Review.

作者信息

Mahat Mohd Muzamir, Sabere Awis Sukarni Mohmad, Azizi Juzaili, Amdan Nur Asyura Nor

机构信息

Textile Research Group, Faculty of Applied Sciences, Universiti Teknologi MARA, 40450 Shah Alam, Selangor Malaysia.

Kulliyyah of Pharmacy, International Islamic University Malaysia, Bandar Indera Mahkota, 25200 Kuantan, Pahang Malaysia.

出版信息

Emergent Mater. 2021;4(1):279-292. doi: 10.1007/s42247-021-00188-4. Epub 2021 Feb 24.

DOI:10.1007/s42247-021-00188-4
PMID:33649739
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7903935/
Abstract

The COVID-19 pandemic is a motivation for material scientists to search for functional materials with valuable properties to alleviate the risks associated with the coronavirus. The formulation of functional materials requires synergistic understanding on the properties of materials and mechanisms of virus transmission and disease progression, including secondary bacterial infections that are prevalent in COVID-19 patients. A viable candidate in the struggle against the pandemic is antimicrobial polymer, due to their favorable properties of flexibility, lightweight, and ease of synthesis. Polymers are the base material for personal protective equipment (PPE), such as gloves, face mask, face shield, and coverall suit for frontliners. Conducting polymers (CPs) are polymers with electrical properties due to the addition of dopant in the polymer structure. The conductivity of polymers augments their antiviral and antibacterial properties. This review discusses the types of CPs and how their properties could be exploited to ward off bacterial infections in hospital settings, specifically in cases involving COVID-19 patients. This review also covers common CPs fabrication techniques. The key components to produce CPs at several possibilities to fit the current needs in fighting secondary bacterial infections are also discussed.

摘要

新冠疫情促使材料科学家寻找具有宝贵特性的功能材料,以降低与冠状病毒相关的风险。功能材料的研发需要对材料特性以及病毒传播和疾病进展机制有协同理解,包括新冠患者中普遍存在的继发性细菌感染。抗菌聚合物是抗击疫情的一个可行候选材料,因为它们具有柔韧性好、重量轻和易于合成等优良特性。聚合物是个人防护装备(PPE)的基础材料,如为一线人员提供的手套、口罩、面罩和工作服。导电聚合物(CPs)是由于在聚合物结构中添加了掺杂剂而具有电学性质的聚合物。聚合物的导电性增强了它们的抗病毒和抗菌性能。本综述讨论了导电聚合物的类型,以及如何利用它们的特性来预防医院环境中的细菌感染,特别是在涉及新冠患者的情况下。本综述还涵盖了常见的导电聚合物制备技术。还讨论了在多种可能性下生产导电聚合物以满足当前抗击继发性细菌感染需求的关键要素。

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