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脊柱脑膜瘤的临床特点:综述。

Clinical Aspects of Spinal Meningiomas: a Review.

机构信息

Sv. Georgi University Hospital, Plovdiv, Bulgaria.

Medical University of Plovdiv, Plovdiv, Bulgaria.

出版信息

Folia Med (Plovdiv). 2021 Feb 28;63(1):24-29. doi: 10.3897/folmed.63.e52967.

Abstract

Spinal meningiomas are found in all age groups, predominantly in women aged over 50 years. The clinical symptoms of this condition may range from mild to significant neurological deficit, varying widely depending on the location, position in relation to the spinal cord, size and histological type of the tumor. Magnetic resonance imaging is the diagnostic tool of choice because it shows the location, size, the axial position of the tumor, and the presence of concomitant conditions such as spinal malformations, edema or syringomyelia.  According to the degree of malignancy, the World Health Organization divides meningiomas into three grades: grade I - benign; grade II - atypical, and grade III - malignant. The goal of the surgery is total resection which is achievable in 82%-98% of cases. Advances in radiosurgery have led to its increased use as primary or adjunct therapy. The current paper aims to review the fundamental clinical as-pects of spinal meningiomas such as their epidemiology, clinical presentation, histological characteristics, diagnostics, and management.

摘要

脊髓脑膜瘤可见于所有年龄段,多见于 50 岁以上女性。该病症的临床表现从轻到重的神经功能缺损不等,差异很大,取决于肿瘤的位置、与脊髓的关系、大小和组织学类型。磁共振成像(MRI)是首选的诊断工具,因为它可以显示肿瘤的位置、大小、轴向位置,以及是否存在脊柱畸形、水肿或脊髓空洞等伴随状况。根据恶性程度,世界卫生组织(WHO)将脑膜瘤分为三级:I 级-良性;II 级-非典型;III 级-恶性。手术的目标是完全切除,82%-98%的病例可以实现。放射外科的进步导致其作为主要或辅助治疗的应用增加。目前的论文旨在回顾脊髓脑膜瘤的基本临床方面,如流行病学、临床表现、组织学特征、诊断和治疗。

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