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通过弱氧配位实现的铑催化双金属碳-氢氧合反应

Rhoda-Electrocatalyzed Bimetallic C-H Oxygenation by Weak O-Coordination.

作者信息

Tan Xuefeng, Massignan Leonardo, Hou Xiaoyan, Frey Johanna, Oliveira João C A, Hussain Masoom Nasiha, Ackermann Lutz

机构信息

Institut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen, Tammannstraße 2, 37077, Göttingen, Germany.

Wöhler Research Institute for Sustainable Chemistry, Georg-August-Universität Göttingen, Tammannstraße 2, 37077, Göttingen, Germany.

出版信息

Angew Chem Int Ed Engl. 2021 Jun 7;60(24):13264-13270. doi: 10.1002/anie.202017359. Epub 2021 May 7.

DOI:10.1002/anie.202017359
PMID:33651910
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8252749/
Abstract

Rhodium-electrocatalyzed arene C-H oxygenation by weakly O-coordinating amides and ketones have been established by bimetallic electrocatalysis. Likewise, diverse dihydrooxazinones were selectively accessed by the judicious choice of current, enabling twofold C-H functionalization. Detailed mechanistic studies by experiment, mass spectroscopy and cyclovoltammetric analysis provided support for an unprecedented electrooxidation-induced C-H activation by a bimetallic rhodium catalysis manifold.

摘要

通过双金属电催化已实现了铑催化的芳烃C-H与弱氧配位酰胺和酮的氧化反应。同样，通过明智地选择电流，可以选择性地得到多种二氢恶嗪酮，实现双重C-H官能化。通过实验、质谱和循环伏安分析进行的详细机理研究，为双金属铑催化体系中前所未有的电氧化诱导C-H活化提供了支持。

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本文引用的文献

1
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2
Insights into Ruthenium(II/IV)-Catalyzed Distal C-H Oxygenation by Weak Coordination.通过弱配位对钌（II/IV）催化的远程C-H氧化反应的见解。
Chemistry. 2020 Dec 9;26(69):16450-16454. doi: 10.1002/chem.202003062. Epub 2020 Oct 29.
3
3d metallaelectrocatalysis for resource economical syntheses.用于资源经济合成的 3d 金属电催化。
Chem Rev. 2023 Oct 11;123(19):11269-11335. doi: 10.1021/acs.chemrev.3c00158. Epub 2023 Sep 26.
4
Electrochemical aromatic C-H hydroxylation in continuous flow.电化学连续流芳香 C-H 羟化。
Nat Commun. 2022 Jul 8;13(1):3945. doi: 10.1038/s41467-022-31634-4.
5
Ruthenaelectro-catalyzed C-H acyloxylation for late-stage tyrosine and oligopeptide diversification.钌电催化的C-H酰氧基化用于晚期酪氨酸和寡肽的多样化修饰
Chem Sci. 2022 Feb 25;13(12):3461-3467. doi: 10.1039/d1sc07267f. eCollection 2022 Mar 24.
Chem Soc Rev. 2020 Jul 6;49(13):4254-4272. doi: 10.1039/d0cs00149j.
4
Insights into Cobalta(III/IV/II)-Electrocatalysis: Oxidation-Induced Reductive Elimination for Twofold C-H Activation.钴（III/IV/II）电催化研究：氧化诱导的还原消除用于双重C-H活化
Angew Chem Int Ed Engl. 2020 Jun 26;59(27):10955-10960. doi: 10.1002/anie.202002258. Epub 2020 May 5.
5
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Acc Chem Res. 2020 Mar 17;53(3):547-560. doi: 10.1021/acs.accounts.9b00529. Epub 2020 Feb 20.
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Acc Chem Res. 2020 Feb 18;53(2):300-310. doi: 10.1021/acs.accounts.9b00603. Epub 2020 Jan 15.
10
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Chem Rev. 2020 Feb 12;120(3):1788-1887. doi: 10.1021/acs.chemrev.9b00495. Epub 2020 Jan 6.