Nuño González A, Magaletskyy K, Martín Carrillo P, Lozano Masdemont B, Mayor Ibarguren A, Feito Rodríguez M, Herranz Pinto P
Servicio de Dermatología, Hospital Universitario La Paz, Madrid, Spain.
SERMAS, Centro de Salud de Colmenarejo, Colmenarejo, Madrid, Spain.
Actas Dermosifiliogr. 2021 Jul-Aug;112(7):640-644. doi: 10.1016/j.ad.2021.02.007. Epub 2021 May 12.
Coronavirus disease 19 (COVID-19) has many manifestations, including respiratory, thrombotic, neurologic, digestive, and cutaneous ones. Cutaneous manifestations have been classified into 5 clinical patterns: acro-ischemic (pseudo-chilblain), vesicular, urticarial, maculopapular, and livedoid. Oral manifestations have also been reported, but much less frequently.
We performed a cross-sectional study in which we examined the oral mucosa of 666 patients with COVID-19 at the IFEMA field hospital in Madrid in April 2020.
Seventy-eight patients (11.7%) had changes involving the oral mucosa. The most common were transient anterior U-shaped lingual papillitis (11.5%) accompanied or not by tongue swelling (6.6%), aphthous stomatitis (6.9%), a burning sensation in the mouth (5.3%), mucositis (3.9%), glossitis with patchy depapillation (3.9%), white tongue (1.6%), and enanthema (0.5%). Most of the patients also reported taste disturbances.
COVID-19 also manifests in the oral cavity. The most common manifestations are transient U-shaped lingual papillitis, glossitis with patchy depapillation, and burning mouth syndrome. Mucositis with or without aphthous ulcers or enanthema may also be observed. Any these findings may be key clues to a diagnosis of COVID-19.
新型冠状病毒肺炎（COVID-19）有多种表现形式，包括呼吸道、血栓形成、神经、消化和皮肤方面的表现。皮肤表现已被分为5种临床类型：肢端缺血型（假冻疮）、水疱型、荨麻疹型、斑丘疹型和类紫癜型。口腔表现也有报道，但频率要低得多。
我们进行了一项横断面研究，于2020年4月在马德里的IFEMA野战医院检查了666例COVID-19患者的口腔黏膜。
78例患者（11.7%）出现口腔黏膜改变。最常见的是短暂性前部U形舌乳头炎（11.5%），伴有或不伴有舌肿胀（6.6%）、复发性阿弗他口炎（6.9%）、口腔烧灼感（5.3%）、黏膜炎（3.9%）、伴有斑片状乳头脱失的舌炎（3.9%）、白舌（1.6%）和黏膜疹（0.5%）。大多数患者还报告有味觉障碍。
COVID-19在口腔也有表现。最常见的表现是短暂性U形舌乳头炎、伴有斑片状乳头脱失的舌炎和灼口综合征。也可能观察到伴有或不伴有阿弗他溃疡或黏膜疹的黏膜炎。这些发现中的任何一项都可能是COVID-19诊断的关键线索。
