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Oral ulcer in SARS-CoV-2 infection: a case report.

作者信息

Rapp Lucie, Gémar Thomas, Lacoste-Ferré Marie-Hélène

机构信息

Dental Faculty and Hospital of Toulouse - Toulouse Institute of Oral Medicine and Science, Centre Hospitalier Universitaire de Toulouse, Toulouse, France.

CERPOP, UMR1295 (Maintain Aging Research Team), Université P. Sabatier, Toulouse, France.

出版信息

AME Case Rep. 2024 Mar 11;8:40. doi: 10.21037/acr-23-158. eCollection 2024.


DOI:10.21037/acr-23-158
PMID:38711897
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11071011/
Abstract

BACKGROUND: The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at the end of 2019 caused the global pandemic. Oral and dermatological manifestations of coronavirus disease 2019 (COVID-19) such as xerostomia, aphthous-like lesions, ulcers, tongue depapillation, necrotizing gingivitis, and taste disorders, including the loss of taste and salivary gland infections are being reported. This study aims to describe a case of oral ulcers following COVID-19 infection. CASE DESCRIPTION: We present the case of a 95-year-old male patient hospitalized in follow-up care and rehabilitation unit, of Minimes Geriatric Clinic, Toulouse, France. He had an alteration in his general health in the context of COVID-19 infection detected by reverse transcription polymerase chain reaction (RT-PCR). Six days after the admission, the patient complained of a strong burning sensation of the mouth, especially on the tongue and the lips' mucosa. Intraoral examination revealed painful erosive areas on the lateral edges of the tongue and the mucous side of the lower lip. The proposed treatment to reduce the burning sensation was based on general analgesics (morphine sulfate), mouthwash with sodium bicarbonate, the application of a lidocaine-based oral anesthetic and healing gel and a comfort-oriented diet. Thirteen days later, the patient reported a gradual improvement. CONCLUSIONS: A diverse range of oral manifestations has been observed in patients with a history of COVID-19 infection. These oral ulcers significantly impact the quality of life of the individual, causing intense pain, stress, and difficulties in eating, with repercussions on nutritional status, especially in older individuals. Our case underscores the importance of oral examinations and the role of dentists in the management of patients with SARS-CoV-2.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adf1/11071011/113865918247/acr-08-23-158-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adf1/11071011/cbbe3a23871c/acr-08-23-158-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adf1/11071011/88076942205c/acr-08-23-158-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adf1/11071011/4a1b98496533/acr-08-23-158-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adf1/11071011/113865918247/acr-08-23-158-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adf1/11071011/cbbe3a23871c/acr-08-23-158-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adf1/11071011/88076942205c/acr-08-23-158-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adf1/11071011/4a1b98496533/acr-08-23-158-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adf1/11071011/113865918247/acr-08-23-158-f4.jpg

相似文献

[1]
Oral ulcer in SARS-CoV-2 infection: a case report.

AME Case Rep. 2024-3-11

[2]
An update on oral clinical courses among patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection: A clinical follow-up (a prospective prevalent cohort) study.

PLoS One. 2022

[3]
Tongue ulcer in a patient with COVID-19: a case presentation.

BMC Oral Health. 2021-5-20

[4]
Oral manifestations of COVID-19 in unvaccinated patients: a cross-sectional study.

BMC Oral Health. 2023-9-27

[5]
Covid-19 and oral diseases: Crosstalk, synergy or association?

Rev Med Virol. 2021-11

[6]
Erythema Multiforme as Early Manifestation of COVID-19: A Case Report.

Pathogens. 2022-6-7

[7]
Oral lesions in patients with SARS-CoV-2 infection: could the oral cavity be a target organ?

Oral Surg Oral Med Oral Pathol Oral Radiol. 2021-2

[8]
COVID-19 and Its Repercussions on Oral Health: A Review.

Medicina (Kaunas). 2021-11-1

[9]
Safety and Efficacy of Imatinib for Hospitalized Adults with COVID-19: A structured summary of a study protocol for a randomised controlled trial.

Trials. 2020-10-28

[10]
A Rare Case of COVID-19-Induced Acute Exacerbation of Oral Dermatitis Herpetiformis in a Geriatric Patient.

Int Med Case Rep J. 2023-3-9

本文引用的文献

[1]
Otolaryngology adverse events following COVID-19 vaccines.

Eur Rev Med Pharmacol Sci. 2022-6

[2]
Oral manifestations in SARS-CoV-2 infection.

Med Oral Patol Oral Cir Bucal. 2022-7-1

[3]
Impact of SARS-CoV-2 on dentistry: a review of literature.

Eur Rev Med Pharmacol Sci. 2022-5

[4]
COVID-19 manifestation in the oral cavity - a narrative literature review.

Acta Otorhinolaryngol Ital. 2021-10

[5]
Morphological alterations in tongue epithelial cells infected by SARS-CoV-2: A case-control study.

Oral Dis. 2022-11

[6]
The 15-Months Clinical Experience of SARS-CoV-2: A Literature Review of Therapies and Adjuvants.

Antioxidants (Basel). 2021-5-31

[7]
Oral manifestations of Covid-19-A literature review.

Rev Med Virol. 2022-1

[8]
Tongue ulcer in a patient with COVID-19: a case presentation.

BMC Oral Health. 2021-5-20

[9]
SARS-CoV-2 Disease through Viral Genomic and Receptor Implications: An Overview of Diagnostic and Immunology Breakthroughs.

Microorganisms. 2021-4-10

[10]
Salivary glands are a target for SARS-CoV-2: a source for saliva contamination.

J Pathol. 2021-7

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