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新型冠状病毒感染中的口腔溃疡:一例报告

Oral ulcer in SARS-CoV-2 infection: a case report.

作者信息

Rapp Lucie, Gémar Thomas, Lacoste-Ferré Marie-Hélène

机构信息

Dental Faculty and Hospital of Toulouse - Toulouse Institute of Oral Medicine and Science, Centre Hospitalier Universitaire de Toulouse, Toulouse, France.

CERPOP, UMR1295 (Maintain Aging Research Team), Université P. Sabatier, Toulouse, France.

出版信息

AME Case Rep. 2024 Mar 11;8:40. doi: 10.21037/acr-23-158. eCollection 2024.

Abstract

BACKGROUND

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at the end of 2019 caused the global pandemic. Oral and dermatological manifestations of coronavirus disease 2019 (COVID-19) such as xerostomia, aphthous-like lesions, ulcers, tongue depapillation, necrotizing gingivitis, and taste disorders, including the loss of taste and salivary gland infections are being reported. This study aims to describe a case of oral ulcers following COVID-19 infection.

CASE DESCRIPTION

We present the case of a 95-year-old male patient hospitalized in follow-up care and rehabilitation unit, of Minimes Geriatric Clinic, Toulouse, France. He had an alteration in his general health in the context of COVID-19 infection detected by reverse transcription polymerase chain reaction (RT-PCR). Six days after the admission, the patient complained of a strong burning sensation of the mouth, especially on the tongue and the lips' mucosa. Intraoral examination revealed painful erosive areas on the lateral edges of the tongue and the mucous side of the lower lip. The proposed treatment to reduce the burning sensation was based on general analgesics (morphine sulfate), mouthwash with sodium bicarbonate, the application of a lidocaine-based oral anesthetic and healing gel and a comfort-oriented diet. Thirteen days later, the patient reported a gradual improvement.

CONCLUSIONS

A diverse range of oral manifestations has been observed in patients with a history of COVID-19 infection. These oral ulcers significantly impact the quality of life of the individual, causing intense pain, stress, and difficulties in eating, with repercussions on nutritional status, especially in older individuals. Our case underscores the importance of oral examinations and the role of dentists in the management of patients with SARS-CoV-2.

摘要

背景

2019年末严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的出现引发了全球大流行。2019冠状病毒病(COVID-19)的口腔和皮肤表现,如口干、口疮样病变、溃疡、舌乳头萎缩、坏死性龈炎以及味觉障碍,包括味觉丧失和唾液腺感染等,均有报道。本研究旨在描述1例COVID-19感染后出现口腔溃疡的病例。

病例描述

我们报告1例95岁男性患者的病例,该患者在法国图卢兹米尼姆斯老年诊所的随访护理和康复单元住院。通过逆转录聚合酶链反应(RT-PCR)检测发现其感染了COVID-19,整体健康状况出现改变。入院6天后,患者主诉口腔有强烈烧灼感,尤其是舌头和唇部黏膜。口腔检查发现舌外侧边缘和下唇黏膜侧有疼痛性糜烂区域。为减轻烧灼感而采取的治疗措施包括使用普通镇痛药(硫酸吗啡)、用碳酸氢钠漱口、涂抹含利多卡因的口腔麻醉剂和愈合凝胶以及给予舒适型饮食。13天后,患者报告症状逐渐改善。

结论

有COVID-19感染史患者出现了多种口腔表现。这些口腔溃疡严重影响个人生活质量,导致剧痛、压力以及进食困难,进而影响营养状况,对老年人尤其如此。我们的病例强调了口腔检查以及牙医在SARS-CoV-2患者管理中的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adf1/11071011/cbbe3a23871c/acr-08-23-158-f1.jpg

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