Prazma J, Smalley W E, Covington S, Pillsbury H C
Division of Otolaryngology/Head and Neck Surgery, University of North Carolina School of Medicine, Chapel Hill 27599-7070.
Arch Otolaryngol Head Neck Surg. 1988 Jun;114(6):657-60. doi: 10.1001/archotol.1988.01860180071033.
The effect of six hours of high-frequency, high-intensity noise exposure on cochlear blood flow (CoBF) was investigated in adult gerbils. The CoBF was measured by microsphere-surface preparation methods. Intracardiac injection of the microspheres (diameter, 11.1 microns; Dupont/New England Nuclear Research Products, Boston) was performed in the last few minutes of the sixth hour of continuous noise exposure, and reference blood was withdrawn from the iliac artery at a rate of 0.165 mL/min. The number of microspheres in the investigated tissue was assessed by direct counting under a microscope. The number of microspheres in the reference blood was counted by a Coulter counter. These experiments have shown that CoBF at the end of six hours of continuous noise exposure does not significantly differ from the CoBF in control animals.
在成年沙鼠中研究了6小时高频高强度噪声暴露对耳蜗血流量（CoBF）的影响。耳蜗血流量通过微球表面制备方法进行测量。在连续噪声暴露的第6小时的最后几分钟内进行心内注射微球（直径11.1微米；杜邦/新英格兰核研究产品公司，波士顿），并以0.165 mL/分钟的速率从髂动脉抽取参比血液。通过显微镜下直接计数评估所研究组织中的微球数量。通过库尔特计数器计算参比血液中的微球数量。这些实验表明，连续噪声暴露6小时结束时的耳蜗血流量与对照动物的耳蜗血流量无显著差异。
