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耳蜗血流。暴露60分钟时噪声的影响。

Cochlear blood flow. The effect of noise at 60 minutes' exposure.

作者信息

Prazma J, Vance S G, Bolster D E, Pillsbury H C, Postma D S

出版信息

Arch Otolaryngol Head Neck Surg. 1987 Jan;113(1):36-9. doi: 10.1001/archotol.1987.01860010040011.

DOI:10.1001/archotol.1987.01860010040011
PMID:3790282
Abstract

The effect of 60 minutes of exposure to high-frequency (10- to 40-kHz), high-intensity (115-dB) noise on the cochlear blood flow (CoBF) was investigated in adult gerbils. The CoBF was measured with a newly improved microsphere method. The number of microspheres in cochlear tissue that had been dissected by the surface preparation technique was assessed by direct counting. Our experiments have indicated that the CoBF is elevated even after 60 minutes of noise exposure. This was true particularly in the areas where these frequencies stimulate the cochlea. The noise also increased CoBF in the opposite ear in areas not corresponding to the stimulation frequencies (second and third turn). This phenomenon is under further investigation.

摘要

研究了成年沙鼠暴露于高频(10至40千赫)、高强度(115分贝)噪声60分钟对耳蜗血流量(CoBF)的影响。采用新改进的微球法测量CoBF。通过直接计数评估经表面制备技术解剖的耳蜗组织中的微球数量。我们的实验表明,即使在噪声暴露60分钟后,CoBF仍会升高。在这些频率刺激耳蜗的区域尤其如此。噪声还使对侧耳中与刺激频率不对应的区域(第二和第三圈)的CoBF增加。这一现象正在进一步研究中。

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