Gastrointestinal Laboratory, Department of Small Animal Clinical Sciences, Texas A&M University, Texas A&M College of Veterinary Medicine & Biomedical Sciences, 4474 TAMU, College Station, TX 77843-4474, USA.
Gastrointestinal Laboratory, Department of Small Animal Clinical Sciences, Texas A&M University, Texas A&M College of Veterinary Medicine & Biomedical Sciences, 4474 TAMU, College Station, TX 77843-4474, USA.
Vet Clin North Am Small Anim Pract. 2021 May;51(3):605-621. doi: 10.1016/j.cvsm.2021.01.002. Epub 2021 Feb 27.
The gut microbiome is a functional organ, and responds metabolically to the nutrient composition within the diet. Fiber, starch, and protein content have strong effects on the microbiome composition, and changes in these nutrient profiles can induce rapid shifts. Due to functional redundancy of bacteria within microbial communities, important metabolites for health can be produced by different bacteria. Microbiome alterations associated with disease are of greater magnitude than those seen in healthy dogs on different diets. Dietary changes, addition of prebiotics, and probiotics, can be beneficial to improve microbial diversity and to normalize metabolite production in diseased dogs.
肠道微生物组是一个功能性器官，会对饮食中的营养成分组成进行代谢反应。纤维、淀粉和蛋白质含量对微生物组组成有很强的影响，这些营养成分的变化会引起快速的转变。由于微生物群落中细菌的功能冗余，不同的细菌可以产生对健康很重要的代谢物。与疾病相关的微生物组改变大于不同饮食下健康犬的改变。饮食改变、添加益生元和益生菌可以改善微生物多样性，并使患病犬的代谢产物恢复正常。
