Javadi Shadi, Khademi Bijan, Mohamadianpanah Mohammad, Shishegar Mahmoud, Babaei Amirhossein
Otolaryngology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Department of Otolaryngology, Khalili Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Iran J Otorhinolaryngol. 2021 Jan;33(114):23-29. doi: 10.22038/ijorl.2020.44283.2463.
Submandibular gland resection is a controversial issue in patients with oral tongue squamous cell carcinomas (SCC). This study aimed to determine the frequency of submandibular gland involvement in patients who had undergone elective submandibular gland resection following oral tongue SCC.
This cross-sectional retrospective study was performed between 2001 and 2017 on patients with oral tongue SCC who had undergone glossectomy in a referral center for otorhinolaryngology surgery, Shiraz, Iran.
In this study, 131 patients were included. Their mean age was 59.84 years (range: 19-86). The mean tumor size was 2.83 cm (range 0.3-7). The vast majority (92%) of the patients were at stage III-IVa and had well (55%) to moderate (31%) differentiated tumor. The mean diameter of the submandibular gland was 3.87 cm (range: 1.5-6 cm). There was only one (0.76%) patient with submandibular involvement. She was an 80-year-old woman with a T2 well differentiated tumor without cervical lymph node involvement in the neck node dissection.
In patients with oral tongue SCC, submandibular gland involvement is rare and its elective resection in not recommended.
对于口腔舌鳞状细胞癌（SCC）患者，下颌下腺切除术是一个存在争议的问题。本研究旨在确定口腔舌SCC患者在接受择期下颌下腺切除术后下颌下腺受累的频率。
本横断面回顾性研究于2001年至2017年对在伊朗设拉子一家耳鼻喉科手术转诊中心接受舌切除术的口腔舌SCC患者进行。
本研究纳入了131例患者。他们的平均年龄为59.84岁（范围：19 - 86岁）。平均肿瘤大小为2.83厘米（范围0.3 - 7厘米）。绝大多数（92%）患者处于III - IVa期，肿瘤分化良好（55%）至中等（31%）。下颌下腺的平均直径为3.87厘米（范围：1.5 - 6厘米）。仅有1例（0.76%）患者出现下颌下腺受累。她是一名80岁女性，患有T2期高分化肿瘤，颈部淋巴结清扫术中未发现颈部淋巴结受累。
对于口腔舌SCC患者，下颌下腺受累罕见，不建议进行择期切除。
