Department of Life Sciences, Dibrugarh Univerity, Dibrugarh, Assam, 786004, India.
Curr Microbiol. 2021 Apr;78(4):1115-1123. doi: 10.1007/s00284-021-02402-2. Epub 2021 Mar 3.
Klebsiella oxytoca is rising as a significant opportunistic pathogen causing nosocomial infections in neonates as well as adults. This pathogen's prevalence varies from 2 to 24%, but outbreaks of infections due to multidrug-resistant strains can be fatal in immunocompromised individuals with comorbidities. Klebsiella oxytoca is responsible for a wide range of ailments from colitis to infective endocarditis, other than the common urinary and respiratory tract infections. The microbe's pathogenicity has been attributed to cytotoxins' production- Tilivalline and Tilimycin, in some intestinal disorders. Klebsiella oxytoca is reported to be resistant to a wide range of antibiotics. Here, we have tried to showcase a brief overview of the emergence of Klebsiella oxytoca in healthcare facilities and the nature of resistance in this species of Klebsiella.
产酸克雷伯菌作为一种重要的机会致病菌,在新生儿和成人中引起医院获得性感染。这种病原体的流行率在 2%到 24%之间,但由于多药耐药株引起的感染爆发,在合并症的免疫功能低下个体中可能是致命的。产酸克雷伯菌可引起多种疾病,从结肠炎到感染性心内膜炎,除了常见的尿路感染和呼吸道感染。该微生物的致病性归因于细胞毒素的产生——在某些肠道疾病中为替利万宁和替利霉素。据报道,产酸克雷伯菌对多种抗生素具有耐药性。在这里,我们试图简要概述产酸克雷伯菌在医疗机构中的出现以及该种克雷伯菌的耐药性。