Department of Midwifery, School of Nursing and Midwifery, Islamic Azad university Ahvaz branch, Ahvaz, Iran.
Department of Midwifery, School of Nursing and Midwifery, Islamic Azad university Bojnourd branch, Bojnourd, Iran.
Adv Exp Med Biol. 2021;1321:299-307. doi: 10.1007/978-3-030-59261-5_27.
In December 2019, a respiratory disease caused by a coronavirus called SARS-CoV-2 (COVID-19) began in Wuhan, China, and quickly became a pandemic. In such situations, pregnant women are suspected of being among the vulnerable groups. The aim of this study was to report clinical symptoms, laboratory findings, and obstetrical complications, maternal, fetal, and neonatal complications of COVID-19 infection in pregnant women. We searched the Cochrane library, MEDLINE/PubMed, and Web of Sciences from their inception to April 5, 2020. Any study involving pregnant women with COVID-19 which evaluated the effect of the disease on pregnancy outcomes and fetal and neonatal complications was included in the study. The outcomes were the symptoms and laboratory findings, obstetrical complications, mode of delivery, and maternal, fetal, and neonatal complications. The search resulted in 69 titles and abstracts, which were narrowed down to 12 studies involving 68 women. The three most common symptoms of patients were fever, cough, and fatigue. The most common laboratory findings were an increase in C-reactive protein (CRP) and lymphopenia. The most common obstetrical complication was preterm labor (33.3%). No maternal deaths were reported. The Cesarean section rate was 83.3% and the vertical transition rate was 2.23%. The findings showed that the clinical symptoms and laboratory measures of pregnant women affected by COVID-19 did not differ from the general population. In general, the prognosis of mothers who suffered from COVID-19 and their newborns was satisfactory. However, there is a need for further rigorous studies to confirm these findings as the pandemic progresses.
2019 年 12 月，一种由冠状病毒 SARS-CoV-2（COVID-19）引起的呼吸道疾病在中国武汉爆发，并迅速成为全球性大流行。在这种情况下，孕妇被怀疑属于弱势群体。本研究旨在报告 COVID-19 感染孕妇的临床症状、实验室检查结果和产科并发症、母婴、胎儿和新生儿并发症。我们检索了 Cochrane 图书馆、MEDLINE/PubMed 和 Web of Sciences 从成立到 2020 年 4 月 5 日的文献。纳入了评估 COVID-19 对妊娠结局和胎儿及新生儿并发症影响的所有研究。结局是症状和实验室检查结果、产科并发症、分娩方式以及母婴、胎儿和新生儿并发症。检索得到 69 个标题和摘要，进一步筛选后纳入 12 项研究，共 68 例孕妇。患者最常见的三种症状是发热、咳嗽和乏力。最常见的实验室检查结果是 C 反应蛋白（CRP）和淋巴细胞减少。最常见的产科并发症是早产（33.3%）。没有孕产妇死亡的报道。剖宫产率为 83.3%，垂直传播率为 2.23%。研究结果表明，受 COVID-19 影响的孕妇的临床症状和实验室检查结果与一般人群无差异。一般来说，患有 COVID-19 的母亲及其新生儿的预后是令人满意的。然而，随着疫情的发展，需要进一步进行严格的研究来证实这些发现。
