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1
Outcomes in adolescent and young adult acute lymphoblastic leukaemia: a report from the Indian Acute Leukaemia Research Database (INwARD) of the Hematology Cancer Consortium (HCC).青少年及青年急性淋巴细胞白血病的治疗结果：血液学癌症联盟（HCC）印度急性白血病研究数据库（INwARD）的报告
Br J Haematol. 2021 Apr;193(1):e1-e4. doi: 10.1111/bjh.17268. Epub 2021 Mar 3.
2
The combination of bortezomib with chemotherapy to treat relapsed/refractory acute lymphoblastic leukaemia of childhood.硼替佐米联合化疗治疗儿童复发/难治性急性淋巴细胞白血病。
Br J Haematol. 2017 Feb;176(4):629-636. doi: 10.1111/bjh.14505. Epub 2017 Jan 24.
3
Risk of late effects of treatment in children newly diagnosed with standard-risk acute lymphoblastic leukaemia: a report from the Childhood Cancer Survivor Study cohort.新诊断为标准风险急性淋巴细胞白血病的儿童治疗后晚期效应的风险：来自儿童癌症幸存者研究队列的报告。
Lancet Oncol. 2014 Jul;15(8):841-51. doi: 10.1016/S1470-2045(14)70265-7. Epub 2014 Jun 19.
4
Outcome of Down syndrome associated acute lymphoblastic leukaemia treated on a contemporary protocol.唐氏综合征相关急性淋巴细胞白血病采用当代方案治疗的结果。
Br J Haematol. 2014 May;165(4):552-5. doi: 10.1111/bjh.12739. Epub 2014 Jan 15.
5
Resource limited centres can deliver treatment for children with acute lymphoblastic leukaemia with risk-stratified minimal residual disease based UKALL 2003 protocol with no modification and a good outcome.资源有限的中心可以按照英国ALL 2003方案，在不对风险分层的微小残留病进行修改的情况下，为急性淋巴细胞白血病儿童提供治疗，且疗效良好。
Expert Rev Hematol. 2020 Oct;13(10):1143-1151. doi: 10.1080/17474086.2020.1813563. Epub 2020 Sep 29.
6
Treatment abandonment in childhood acute lymphoblastic leukaemia in China: a retrospective cohort study of the Chinese Children's Cancer Group.中国儿童癌症协作组关于儿童急性淋巴细胞白血病治疗中断的回顾性队列研究。
Arch Dis Child. 2019 Jun;104(6):522-529. doi: 10.1136/archdischild-2018-316181. Epub 2019 Jan 31.
7
Outcome of adolescent patients with acute lymphoblastic leukaemia aged 10-14 years as compared with those aged 15-17 years: Long-term results of 1094 patients of the AIEOP-BFM ALL 2000 study.10-14 岁与 15-17 岁青少年急性淋巴细胞白血病患者的结局比较：AIEOP-BFM ALL 2000 研究 1094 例患者的长期结果。
Eur J Cancer. 2019 Nov;122:61-71. doi: 10.1016/j.ejca.2019.09.004. Epub 2019 Oct 17.
8
Challenges of starting treatment protocols for acute lymphoblastic leukaemia in a low-income setting - the Blantyre experience.在低收入环境中启动急性淋巴细胞白血病治疗方案面临的挑战——布兰太尔经验
Br J Haematol. 2020 Nov;191(3):e87-e90. doi: 10.1111/bjh.17040. Epub 2020 Aug 17.
9
Early morphological response is significantly associated with, but does not accurately predict, relapse in teenagers and young adults aged 10-24 years with acute lymphoblastic leukaemia (ALL): results from UKALL2003.早期形态学反应与10至24岁青少年及年轻成人急性淋巴细胞白血病（ALL）的复发显著相关，但不能准确预测复发情况：英国ALL2003研究结果
Br J Haematol. 2019 Feb;184(4):663-666. doi: 10.1111/bjh.15150. Epub 2018 Feb 22.
10
Nelarabine, intensive L-asparaginase, and protracted intrathecal therapy for newly diagnosed T-cell acute lymphoblastic leukaemia in children and young adults (ALL-T11): a nationwide, multicenter, phase 2 trial including randomisation in the very high-risk group.尼拉滨、大剂量 L-门冬酰胺酶和延长鞘内治疗新诊断的儿童和青年急性 T 淋巴细胞白血病（ALL-T11）：一项全国性、多中心、2 期试验，包括极高危组的随机分组。
Lancet Haematol. 2023 Jun;10(6):e419-e432. doi: 10.1016/S2352-3026(23)00072-8. Epub 2023 May 8.

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Adoptive Cellular Therapies in Pediatric Leukemia Patients After Allogeneic-Hematopoietic Stem Cell Transplants.异基因造血干细胞移植后儿童白血病患者的过继性细胞疗法
Immune Netw. 2025 Aug 12;25(4):e29. doi: 10.4110/in.2025.25.e29. eCollection 2025 Aug.
2
The evolving therapeutic revolution in adult acute lymphoblastic leukemia.成人急性淋巴细胞白血病不断发展的治疗革命。
Cancer. 2025 May 15;131(10):e35872. doi: 10.1002/cncr.35872.
3
Safety and Feasibility of Hippocampal Sparing Cranial Radiation in Pediatric and Adolescent Acute Lymphoblastic Leukemia Patients: A Prospective Study.小儿和青少年急性淋巴细胞白血病患者海马区 sparing 全脑放疗的安全性和可行性：一项前瞻性研究
Cureus. 2024 Jun 19;16(6):e62715. doi: 10.7759/cureus.62715. eCollection 2024 Jun.
4
Minimal Residual Disease in the Management of B-Cell Acute Lymphoblastic Leukemia: A Systematic Review of Studies from Indian Settings.B 细胞急性淋巴细胞白血病治疗中的微小残留病：来自印度地区研究的系统评价
Indian J Hematol Blood Transfus. 2024 Jan;40(1):1-11. doi: 10.1007/s12288-023-01641-6. Epub 2023 Mar 30.
5
Pediatric-Inspired Regimens in the Treatment of Acute Lymphoblastic Leukemia in Adolescents and Young Adults: A Systematic Review.青少年和年轻成人急性淋巴细胞白血病治疗中受儿科启发的方案：一项系统评价
Curr Oncol. 2023 Sep 20;30(9):8612-8632. doi: 10.3390/curroncol30090625.
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Management of B-cell lineage acute lymphoblastic leukemia: expert opinion from an Indian panel Delphi consensus method.B细胞系急性淋巴细胞白血病的管理：印度专家小组的专家意见 德尔菲共识法
Front Oncol. 2023 Apr 24;13:1171568. doi: 10.3389/fonc.2023.1171568. eCollection 2023.
7
Survival benefit of pediatric-based regimen for adults with acute lymphoblastic leukemia: A single-center retrospective cohort.基于儿科方案对成人急性淋巴细胞白血病患者的生存获益：一项单中心回顾性队列研究。
Hematol Transfus Cell Ther. 2023 Jul;45 Suppl 2(Suppl 2):S18-S24. doi: 10.1016/j.htct.2021.08.016. Epub 2021 Dec 9.
8
Precursor B-cell acute lymphoblastic leukaemia-a global view.前体 B 细胞急性淋巴细胞白血病——全球视角。
Br J Haematol. 2022 Feb;196(3):530-547. doi: 10.1111/bjh.17959. Epub 2021 Dec 20.
9
Outcomes and prognostic factors in adolescents and young adults with ALL treated with a modified BFM-90 protocol.采用改良 BFM-90 方案治疗 ALL 的青少年和年轻成人的结果和预后因素。
Blood Adv. 2021 Mar 9;5(5):1178-1193. doi: 10.1182/bloodadvances.2020003526.

本文引用的文献

1
Overview of Adolescent and Young Adult Oncology.青少年与青年肿瘤学概述
J Oncol Pract. 2019 May;15(5):235-237. doi: 10.1200/JOP.19.00075. Epub 2019 Apr 22.
2
The effect of adopting pediatric protocols in adolescents and young adults with acute lymphoblastic leukemia in pediatric vs adult centers: An IMPACT Cohort study.儿科方案在儿科与成人中心治疗青少年和年轻成人急性淋巴细胞白血病中的效果：IMPACT 队列研究。
Cancer Med. 2019 May;8(5):2095-2103. doi: 10.1002/cam4.2096. Epub 2019 Mar 26.
3
A pediatric regimen for older adolescents and young adults with acute lymphoblastic leukemia: results of CALGB 10403.一项针对急性淋巴细胞白血病的大龄青少年和年轻成人的儿科治疗方案：CALGB 10403 研究结果。
Blood. 2019 Apr 4;133(14):1548-1559. doi: 10.1182/blood-2018-10-881961. Epub 2019 Jan 18.
4
Adult Acute Lymphoblastic Leukemia: Limitations of Intensification of Therapy in a Developing Country.成人急性淋巴细胞白血病：发展中国家强化治疗的局限性
J Glob Oncol. 2018 Sep;4:1-12. doi: 10.1200/JGO.17.00014.
5
Acute Lymphoblastic Leukemia in Young Adults Treated with Intensive "Pediatric" Type Protocol.采用强化“儿科”类型方案治疗的年轻成人急性淋巴细胞白血病
Indian J Hematol Blood Transfus. 2018 Jul;34(3):422-429. doi: 10.1007/s12288-017-0892-y. Epub 2017 Oct 17.
6
Patterns of care and outcomes in adolescent and young adult acute lymphoblastic leukemia: a population-based study.青少年和年轻成人急性淋巴细胞白血病的治疗模式和结局：一项基于人群的研究。
Blood Adv. 2018 Apr 24;2(8):895-903. doi: 10.1182/bloodadvances.2017014944.
7
Acute lymphoblastic leukemia in adolescents and young adults.青少年和青年急性淋巴细胞白血病
Cancer. 2017 Jul 1;123(13):2398-2403. doi: 10.1002/cncr.30624. Epub 2017 Mar 22.
8
Pegylated-asparaginase during induction therapy for adult acute lymphoblastic leukaemia: toxicity data from the UKALL14 trial.聚乙二醇化天冬酰胺酶用于成人急性淋巴细胞白血病诱导治疗：来自UKALL14试验的毒性数据。
Leukemia. 2017 Jan;31(1):58-64. doi: 10.1038/leu.2016.219. Epub 2016 Aug 2.
9
Final results of a single institution experience with a pediatric-based regimen, the augmented Berlin-Frankfurt-Münster, in adolescents and young adults with acute lymphoblastic leukemia, and comparison to the hyper-CVAD regimen.一项针对青少年和年轻成人急性淋巴细胞白血病的基于儿科方案（强化柏林-法兰克福-明斯特方案）的单机构经验的最终结果，以及与高剂量环磷酰胺、长春新碱、多柔比星和地塞米松（Hyper-CVAD）方案的比较。
Am J Hematol. 2016 Aug;91(8):819-23. doi: 10.1002/ajh.24419. Epub 2016 Jun 30.
10
Efficacy and toxicity of a paediatric protocol in teenagers and young adults with Philadelphia chromosome negative acute lymphoblastic leukaemia: results from UKALL 2003.一项针对费城染色体阴性急性淋巴细胞白血病青少年和年轻成人的儿科方案的疗效与毒性：英国ALL 2003研究结果
Br J Haematol. 2016 Feb;172(3):439-51. doi: 10.1111/bjh.13847. Epub 2015 Dec 18.

Outcomes in adolescent and young adult acute lymphoblastic leukaemia: a report from the Indian Acute Leukaemia Research Database (INwARD) of the Hematology Cancer Consortium (HCC).

作者信息

Ganesan Prasanth, Jain Hasmukh, Bagal Bhausaheb, Subramanian Papagudi G, George Biju, Korula Anu, Mehra Nikita, Kalaiyarasi Jayachandran P, Bhurani Dinesh, Agrawal Narendra, Ahmed Rayaz, Kayal Smita, Bhattacharyya Jina, Yanamandra Uday, Kumar Suman, Philip Chepsy C, John M Joseph, Nadaraj Ambily, Karunamurthy Omprakash, Lakshmanan Jeyaseelan, Mathews Vikram, Sengar Manju

机构信息

Department of Medical Oncology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.

Department of Medical Oncology, Adult Hematolymphoid Disease Management Group, Tata Memorial Centre, Mumbai, India.

出版信息

Br J Haematol. 2021 Apr;193(1):e1-e4. doi: 10.1111/bjh.17268. Epub 2021 Mar 3.

DOI:10.1111/bjh.17268
PMID:33656752
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7610916/
Abstract
摘要