Department of Pharmaceutical Sciences, University of Colorado Skaggs School of Pharmacy & Pharmaceutical Sciences, Aurora, CO 80045, USA.
Department of Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy & Pharmaceutical Sciences, Aurora, CO 80045, USA.
Pharmacogenomics. 2021 Apr;22(5):263-274. doi: 10.2217/pgs-2020-0112. Epub 2021 Mar 4.
To assess providers' knowledge, attitudes, perceptions, and experiences related to pharmacogenomic (PGx) testing in pediatric patients. An electronic survey was sent to multidisciplinary healthcare providers at a pediatric hospital. Of 261 respondents, 71.3% were slightly or not at all familiar with PGx, despite 50.2% reporting prior PGx education or training. Most providers, apart from psychiatry, perceived PGx to be at least moderately useful to inform clinical decisions. However, only 26.4% of providers had recent PGx testing experience. Unfamiliarity with PGx and uncertainty about the clinical value of testing were common perceived challenges. Low PGx familiarity among pediatric providers suggests additional education and electronic resources are needed for PGx examples in which data support testing in children.
为了评估医疗服务提供者在儿科患者中与药物基因组学（PGx）检测相关的知识、态度、看法和经验。我们向一家儿童医院的多学科医疗服务提供者发送了一份电子调查。在 261 名受访者中，尽管 50.2%的人报告了之前的 PGx 教育或培训，但只有 71.3%的人对 PGx 略有了解或完全不了解。除了精神病学以外，大多数医疗服务提供者认为 PGx 至少在一定程度上有助于为临床决策提供信息。然而，只有 26.4%的医疗服务提供者具有最近的 PGx 检测经验。对 PGx 不熟悉以及对检测临床价值的不确定性是普遍存在的认知挑战。儿科医疗服务提供者对 PGx 的熟悉程度较低，这表明需要提供更多的教育和电子资源，以便在有数据支持儿童检测的情况下，了解 PGx 实例。
