MGH Institute of Health Professions, Charlestown, MA 02129, USA.
Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
Pharmacogenomics. 2023 Jul;24(10):539-549. doi: 10.2217/pgs-2023-0039. Epub 2023 Jul 17.
To understand how attitudes toward pharmacogenomic (PGx) testing among healthcare providers varies by specialty. Providers reported comfort ordering PGx testing and its perceived utility on web-based surveys before and after genetics education. Primary quantitative analyses compared primary care providers (PCPs) to specialty providers at both timepoints. PCPs were more likely than specialty care providers to rate PGx testing as useful at both timepoints. Education increased comfort ordering PGx tests, with larger improvements among PCPs than specialty providers. Over 90% of cardiology and internal medicine providers rated PGx testing as useful at pre- and post-education. PCPs overwhelmingly perceive PGx to be useful, and provider education is particularly effective for improving PCPs' confidence. Education for all specialties will be essential to ensure appropriate integration into routine practice.
为了了解医疗保健提供者对药物基因组学（PGx）检测的态度如何因专业而异。在接受基因教育前后，医疗保健提供者通过在线调查来报告他们对 PGx 检测的舒适度和感知实用性。主要的定量分析在两个时间点上比较了初级保健提供者（PCP）和专科提供者。在两个时间点上，PCP 比专科医疗保健提供者更有可能认为 PGx 检测有用。教育增加了对 PGx 检测的订购意愿，PCP 的改善幅度大于专科提供者。超过 90%的心脏病学和内科医生认为在教育前后 PGx 检测都有用。PCP 绝大多数认为 PGx 检测有用，而提供者教育对于提高 PCP 的信心特别有效。为了确保将其适当整合到常规实践中，所有专业的教育都将是必不可少的。
