• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

颈动脉粥样硬化的血浆蛋白谱与动脉粥样硬化结局:荟萃分析和孟德尔随机分析。

Plasma Protein Profile of Carotid Artery Atherosclerosis and Atherosclerotic Outcomes: Meta-Analyses and Mendelian Randomization Analyses.

机构信息

Department of Medical Sciences, Uppsala University, Sweden (L.L., J.S.).

Unit of Cardiovascular Medicine, Department of Medicine, Karolinska Institutet, Sweden (B.G., A.H., A.M.).

出版信息

Arterioscler Thromb Vasc Biol. 2021 May 5;41(5):1777-1788. doi: 10.1161/ATVBAHA.120.315597. Epub 2021 Mar 4.

DOI:10.1161/ATVBAHA.120.315597
PMID:33657885
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8062283/
Abstract

[Figure: see text].

摘要

[图:见正文]。

相似文献

1
Plasma Protein Profile of Carotid Artery Atherosclerosis and Atherosclerotic Outcomes: Meta-Analyses and Mendelian Randomization Analyses.颈动脉粥样硬化的血浆蛋白谱与动脉粥样硬化结局:荟萃分析和孟德尔随机分析。
Arterioscler Thromb Vasc Biol. 2021 May 5;41(5):1777-1788. doi: 10.1161/ATVBAHA.120.315597. Epub 2021 Mar 4.
2
Lipoprotein-associated phospholipase A2 is related to risk of subclinical atherosclerosis but is not supported by Mendelian randomization analysis in a general Japanese population.脂蛋白相关磷脂酶A2与亚临床动脉粥样硬化风险相关,但在一般日本人群中未得到孟德尔随机化分析的支持。
Atherosclerosis. 2016 Mar;246:141-7. doi: 10.1016/j.atherosclerosis.2015.12.027. Epub 2015 Dec 23.
3
Effects of Genetically Determined Iron Status on Risk of Venous Thromboembolism and Carotid Atherosclerotic Disease: A Mendelian Randomization Study.遗传铁状态对静脉血栓栓塞和颈动脉粥样硬化疾病风险的影响:一项孟德尔随机化研究。
J Am Heart Assoc. 2019 Aug 6;8(15):e012994. doi: 10.1161/JAHA.119.012994. Epub 2019 Jul 16.
4
Cadmium, Carotid Atherosclerosis, and Incidence of Ischemic Stroke.镉、颈动脉粥样硬化与缺血性脑卒中的发生。
J Am Heart Assoc. 2017 Dec 2;6(12):e006415. doi: 10.1161/JAHA.117.006415.
5
Use of a proximity extension assay proteomics chip to discover new biomarkers for human atherosclerosis.使用邻近延伸分析蛋白质组学芯片发现人类动脉粥样硬化的新生物标志物。
Atherosclerosis. 2015 Sep;242(1):205-10. doi: 10.1016/j.atherosclerosis.2015.07.023. Epub 2015 Jul 14.
6
Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease.脂联素对颈动脉内膜中层厚度及心血管疾病发病的性别特异性影响
J Am Heart Assoc. 2015 Aug 14;4(8):e001853. doi: 10.1161/JAHA.115.001853.
7
Increased carotid plaque burden in men with the fibrillin-1 2/3 genotype.携带原纤蛋白-1 2/3基因型的男性颈动脉斑块负担增加。
Clin Exp Pharmacol Physiol. 2014 Sep;41(9):637-42. doi: 10.1111/1440-1681.12259.
8
CD34+/CD144+ circulating endothelial cells as an indicator of carotid atherosclerosis.CD34+/CD144+循环内皮细胞作为颈动脉粥样硬化的一个指标
J Stroke Cerebrovasc Dis. 2015 Mar;24(3):583-90. doi: 10.1016/j.jstrokecerebrovasdis.2014.10.001. Epub 2014 Dec 23.
9
High-resolution radial artery intima-media thickness and cardiovascular risk factors in patients with suspected coronary artery disease--comparison with common carotid artery intima-media thickness.高分辨率桡动脉内中膜厚度与疑似冠心病患者心血管危险因素的相关性——与颈总动脉内中膜厚度的比较。
Atherosclerosis. 2012 Mar;221(1):118-23. doi: 10.1016/j.atherosclerosis.2011.12.035. Epub 2011 Dec 29.
10
Associations of matrix metalloproteinase-9 and monocyte chemoattractant protein-1 concentrations with carotid atherosclerosis, based on measurements of plaque and intima-media thickness.基于斑块和内-中膜厚度测量,基质金属蛋白酶-9 和单核细胞趋化蛋白-1 浓度与颈动脉粥样硬化的相关性。
Atherosclerosis. 2014 Jan;232(1):199-203. doi: 10.1016/j.atherosclerosis.2013.11.040. Epub 2013 Nov 25.

引用本文的文献

1
Potential drug targets for peripheral artery disease identified through Mendelian randomization analysis.通过孟德尔随机化分析确定的外周动脉疾病潜在药物靶点。
Thromb J. 2025 May 20;23(1):52. doi: 10.1186/s12959-025-00738-4.
2
Mendelian randomization reveals plasminogen as a common therapeutic target for myocardial infarction and atrial fibrillation.孟德尔随机化研究表明,纤溶酶原是心肌梗死和心房颤动的共同治疗靶点。
J Cardiovasc Thorac Res. 2024;16(4):249-257. doi: 10.34172/jcvtr.33269. Epub 2024 Dec 23.
3
Plasma proteome and incident myocardial infarction: sex-specific differences.血浆蛋白质组与心肌梗死事件:性别特异性差异。
Eur Heart J. 2024 Nov 14;45(43):4647-4657. doi: 10.1093/eurheartj/ehae658.
4
Measured and genetically predicted protein levels and cardiovascular diseases in UK Biobank and China Kadoorie Biobank.在英国生物库和中国科爱瑞生物库中测量和遗传预测的蛋白质水平与心血管疾病。
Nat Cardiovasc Res. 2024 Oct;3(10):1189-1198. doi: 10.1038/s44161-024-00545-6. Epub 2024 Sep 25.
5
Prognostic effect of osteoprotegerin in patients with ischemic stroke: A systematic review and meta-analysis.骨保护素对缺血性脑卒中患者预后的影响:系统评价和荟萃分析。
PLoS One. 2024 May 31;19(5):e0303832. doi: 10.1371/journal.pone.0303832. eCollection 2024.
6
Transcriptomic-based clustering of human atherosclerotic plaques identifies subgroups with different underlying biology and clinical presentation.基于转录组学的人类动脉粥样硬化斑块聚类可识别出具有不同潜在生物学特性和临床表现的亚组。
Nat Cardiovasc Res. 2022 Dec;1(12):1140-1155. doi: 10.1038/s44161-022-00171-0. Epub 2022 Dec 12.
7
Circulating proteins and peripheral artery disease risk: observational and Mendelian randomization analyses.循环蛋白与外周动脉疾病风险:观察性研究与孟德尔随机化分析
Eur Heart J Open. 2023 May 30;3(3):oead056. doi: 10.1093/ehjopen/oead056. eCollection 2023 May.
8
Plasma Proteomic Associations With Incident Ischemic Stroke in Older Adults: The Cardiovascular Health Study.老年人中与缺血性卒中事件相关的血浆蛋白质组学:心血管健康研究。
Neurology. 2023 May 23;100(21):e2182-e2190. doi: 10.1212/WNL.0000000000207242. Epub 2023 Apr 4.
9
Impaired sensitivity to thyroid hormones and carotid plaque in patients with coronary heart disease: A RCSCD-TCM study in China.中国 RCSCD-TCM 研究:冠心病患者对甲状腺激素敏感性降低与颈动脉斑块。
Front Endocrinol (Lausanne). 2022 Sep 27;13:940633. doi: 10.3389/fendo.2022.940633. eCollection 2022.
10
Carpal Tunnel Syndrome and Ulnar Nerve Entrapment at the Elbow Are Not Associated With Plasma Levels of Caspase-3, Caspase-8 or HSP27.腕管综合征和肘部尺神经卡压与半胱天冬酶-3、半胱天冬酶-8或热休克蛋白27的血浆水平无关。
Front Neurosci. 2022 Mar 4;16:809537. doi: 10.3389/fnins.2022.809537. eCollection 2022.

本文引用的文献

1
Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals.对 30931 个人的 90 种心血管蛋白进行基因组和药物靶点评估。
Nat Metab. 2020 Oct;2(10):1135-1148. doi: 10.1038/s42255-020-00287-2. Epub 2020 Oct 16.
2
The plasma protein profile and cardiovascular risk differ between intima-media thickness of the common carotid artery and the bulb: A meta-analysis and a longitudinal evaluation.颈总动脉和颈动脉窦处内-中膜厚度的血浆蛋白谱及心血管风险不同:荟萃分析及纵向评估。
Atherosclerosis. 2020 Feb;295:25-30. doi: 10.1016/j.atherosclerosis.2020.01.011. Epub 2020 Jan 18.
3
Voxel-wise Study of Cohort Associations in Whole-Body MRI: Application in Metabolic Syndrome and Its Components.体素-wise 研究全身体 MRI 队列关联:代谢综合征及其组分的应用。
Radiology. 2020 Mar;294(3):559-567. doi: 10.1148/radiol.2019191035. Epub 2019 Dec 31.
4
Matrix Metalloproteinases in COPD and atherosclerosis with emphasis on the effects of smoking.COPD 和动脉粥样硬化中的基质金属蛋白酶,重点介绍吸烟的影响。
PLoS One. 2019 Feb 21;14(2):e0211987. doi: 10.1371/journal.pone.0211987. eCollection 2019.
5
High Levels of Soluble Lectinlike Oxidized Low-Density Lipoprotein Receptor-1 Are Associated With Carotid Plaque Inflammation and Increased Risk of Ischemic Stroke.高水平的可溶性凝集素样氧化型低密度脂蛋白受体-1 与颈动脉斑块炎症和缺血性卒中风险增加相关。
J Am Heart Assoc. 2019 Feb 19;8(4):e009874. doi: 10.1161/JAHA.118.009874.
6
Plasma levels of apolipoproteins C-III, A-IV, and E are independently associated with stable atherosclerotic cardiovascular disease.载脂蛋白 C-III、A-IV 和 E 的血浆水平与稳定的动脉粥样硬化性心血管疾病独立相关。
Atherosclerosis. 2019 Feb;281:17-24. doi: 10.1016/j.atherosclerosis.2018.11.006. Epub 2018 Nov 9.
7
GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.GWAS 和共定位分析提示颈动脉内膜中层厚度和颈动脉斑块部位与心血管结局相关。
Nat Commun. 2018 Dec 3;9(1):5141. doi: 10.1038/s41467-018-07340-5.
8
Relationship between low levels of circulating TRAIL and atheromatosis progression in patients with chronic kidney disease.慢性肾脏病患者循环 TRAIL 水平低与动脉粥样硬化进展的关系。
PLoS One. 2018 Sep 11;13(9):e0203716. doi: 10.1371/journal.pone.0203716. eCollection 2018.
9
Matrix metalloproteinases in pro-atherosclerotic arterial remodeling.基质金属蛋白酶在动脉粥样硬化前动脉重构中的作用。
J Mol Cell Cardiol. 2018 Oct;123:159-167. doi: 10.1016/j.yjmcc.2018.08.026. Epub 2018 Aug 30.
10
Serum Proteomic Profiling to Identify Biomarkers of Premature Carotid Atherosclerosis.血清蛋白质组学分析鉴定颈动脉粥样硬化早期的生物标志物
Sci Rep. 2018 Jun 15;8(1):9209. doi: 10.1038/s41598-018-27265-9.