系统医学术语入门：早期研究者指南

An Early Stage Researcher's Primer on Systems Medicine Terminology.

作者信息

Zanin Massimiliano, Aitya Nadim A A, Basilio José, Baumbach Jan, Benis Arriel, Behera Chandan K, Bucholc Magda, Castiglione Filippo, Chouvarda Ioanna, Comte Blandine, Dao Tien-Tuan, Ding Xuemei, Pujos-Guillot Estelle, Filipovic Nenad, Finn David P, Glass David H, Harel Nissim, Iesmantas Tomas, Ivanoska Ilinka, Joshi Alok, Boudjeltia Karim Zouaoui, Kaoui Badr, Kaur Daman, Maguire Liam P, McClean Paula L, McCombe Niamh, de Miranda João Luís, Moisescu Mihnea Alexandru, Pappalardo Francesco, Polster Annikka, Prasad Girijesh, Rozman Damjana, Sacala Ioan, Sanchez-Bornot Jose M, Schmid Johannes A, Sharp Trevor, Solé-Casals Jordi, Spiwok Vojtěch, Spyrou George M, Stalidzans Egils, Stres Blaž, Sustersic Tijana, Symeonidis Ioannis, Tieri Paolo, Todd Stephen, Van Steen Kristel, Veneva Milena, Wang Da-Hui, Wang Haiying, Wang Hui, Watterson Steven, Wong-Lin KongFatt, Yang Su, Zou Xin, Schmidt Harald H H W

机构信息

Centro de Tecnología Biomédica, Universidad Politécnica de Madrid, Madrid, Spain.

Intelligent Systems Research Centre, School of Computing, Engineering and Intelligent Systems, Ulster University, Ulster, United Kingdom.

出版信息

Netw Syst Med. 2021 Feb 25;4(1):2-50. doi: 10.1089/nsm.2020.0003. eCollection 2021 Feb.

DOI:10.1089/nsm.2020.0003

PMID:33659919

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7919422/

Abstract

Systems Medicine is a novel approach to medicine, that is, an interdisciplinary field that considers the human body as a system, composed of multiple parts and of complex relationships at multiple levels, and further integrated into an environment. Exploring Systems Medicine implies understanding and combining concepts coming from diametral different fields, including medicine, biology, statistics, modeling and simulation, and data science. Such heterogeneity leads to semantic issues, which may slow down implementation and fruitful interaction between these highly diverse fields. In this review, we collect and explain more than100 terms related to Systems Medicine. These include both modeling and data science terms and basic systems medicine terms, along with some synthetic definitions, examples of applications, and lists of relevant references. This glossary aims at being a first aid kit for the Systems Medicine researcher facing an unfamiliar term, where he/she can get a first understanding of them, and, more importantly, examples and references for digging into the topic.

摘要

系统医学是一种全新的医学方法，也就是说，它是一个跨学科领域，将人体视为一个由多个部分组成、在多个层面存在复杂关系并进一步融入一个环境的系统。探索系统医学意味着理解和整合来自截然不同领域的概念，包括医学、生物学、统计学、建模与仿真以及数据科学。这种异质性会引发语义问题，这可能会减缓这些高度多样化领域之间的实施进程和富有成效的互动。在本综述中，我们收集并解释了100多个与系统医学相关的术语。这些术语既包括建模和数据科学术语，也包括基本的系统医学术语，同时还有一些综合定义、应用示例以及相关参考文献列表。本术语表旨在为面对陌生术语的系统医学研究人员提供一个急救包，在这里他们可以对这些术语有初步的理解，更重要的是，还能找到深入探究该主题的示例和参考文献。