Sicard N, Bouvier F
J Bacteriol. 1977 Dec;132(3):779-83. doi: 10.1128/jb.132.3.779-783.1977.
The interference of dnaB mutations of Escherichia coli with thymineless death is described. All the isogenic Thy- dnaB mutants of E. coli we have tested show a remarkable immunity towards cell death induced by thymine deprivation at the nonpermissive temperature. We have also constructed and tested an isogenic double dnaB dnaG mutant. It loses its viability in the absence of thymine at both permissive and nonpermissive temperatures. The role of the dnaB gene product is discussed.
描述了大肠杆菌dnaB突变对无胸腺死亡的干扰。我们测试的所有大肠杆菌同基因Thy - dnaB突变体在非允许温度下对胸腺嘧啶剥夺诱导的细胞死亡都表现出显著的抗性。我们还构建并测试了一个同基因双dnaB dnaG突变体。它在允许温度和非允许温度下,在没有胸腺嘧啶的情况下都会失去活力。讨论了dnaB基因产物的作用。