Division of Urology, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon.
Division of General Surgery, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon.
Investig Clin Urol. 2021 Mar;62(2):210-216. doi: 10.4111/icu.20200249.
Aquablation is a new technology that relies on real-time ultrasound guidance to ablate prostatic tissues using high velocity pressurized water. We hereby present our data and experience in this technique by exploring the perioperative surgical and functional outcomes.
This is a prospectively filled study including consecutive patients who underwent aquablation at our Middle Eastern tertiary care center. Patient demographics, voiding parameters, and prostate disease specific variables were collected. We reported on the surgical and functional outcomes as well as the 3-month adverse events. We also explored the trend in hemoglobin drop and hemostasis method by dividing the consecutive cases into four temporal periods.
Fifty-nine patients underwent aquablation between March 2018 and March 2020. Mean time from transrectal ultrasound to Foley insertion was 48.5±2.5 minutes. Cautery was performed in 35 patients (59.3%) and a catheter-tensioning device was mounted in 50 patients (84.7%). On average, the hemoglobin dropped by -1.7±0.2 ng/dL (p<0.0001). The average length of catheterization and hospital stay were 2.1±0.3 days and 2.2±0.1 days, respectively. Only three patients (5.1%) were re-hospitalized. At three months, the average drop in serum prostate-specific antigen was -36.6±6.0% (p<0.0001) and functional outcomes considerably improved. We also recorded 14 adverse events in 13 patients (overall rate of 22.0%), with grade 1 and grade 2 complications comprising 71.4% of all adverse events.
Our study results confirm the safety and efficacy of the aquablation procedure in the adoption phase.
水刀消融是一种新的技术,它依赖于实时超声引导,使用高速加压水来消融前列腺组织。我们在此通过探索围手术期的手术和功能结果,介绍该技术的数据和经验。
这是一项前瞻性的研究,包括在我们中东的三级保健中心接受水刀消融的连续患者。收集患者的人口统计学资料、排尿参数和前列腺疾病特定变量。我们报告了手术和功能结果以及 3 个月的不良事件。我们还通过将连续病例分为四个时期来探讨血红蛋白下降和止血方法的趋势。
59 例患者于 2018 年 3 月至 2020 年 3 月期间接受水刀消融。从经直肠超声到 Foley 插入的平均时间为 48.5±2.5 分钟。35 例(59.3%)患者行电凝术,50 例(84.7%)患者安装导管张力装置。平均血红蛋白下降-1.7±0.2ng/dL(p<0.0001)。导管留置和住院时间的平均长度分别为 2.1±0.3 天和 2.2±0.1 天。仅 3 例(5.1%)患者再次住院。三个月时,血清前列腺特异性抗原平均下降-36.6±6.0%(p<0.0001),功能结果显著改善。我们还记录了 13 例患者中的 14 例不良事件(总发生率为 22.0%),其中 1 级和 2 级并发症占所有不良事件的 71.4%。
我们的研究结果证实了水刀消融程序在采用阶段的安全性和有效性。