Bach Thorsten, Gilling Peter, El Hajj Albert, Anderson Paul, Barber Neil
Asklepios Westklinikum Hamburg-Rissen, 22559 Hamburg, Germany.
Tauranga Urology Research Ltd, 3112 Tauranga, New Zealand.
J Clin Med. 2020 Feb 24;9(2):603. doi: 10.3390/jcm9020603.
Waterjet-based prostate resection (Aquablation procedure) is an increasingly recognized treatment for symptomatic benign prostatic hyperplasia (BPH). We confirmed the safety and effectiveness of the Aquablation procedure in the commercial setting in 178 men at five sites. The mean prostate volume was 59 cc. The procedure time averaged 24 min and total anesthesia duration was 50 min. The International Prostate Symptom Score (IPSS) decreased from 21.6 at the baseline to 6.5 at the 12-month follow-up, a 15.3-point improvement ( < 0.0001). The maximum urinary flow rate increased from 10 cc/s at the baseline to 20.8 cc/s at month 12 (increase of 11.8 cc, < 0.0001). Ejaculatory function was relatively preserved. Prostate volume assessed with transrectal ultrasound decreased 36% by month three. Five patients (2.7%) underwent a transfusion in the first week after the procedure. Real-world evidence shows that Aquablation is safe and effective for the treatment of BPH.
基于水刀的前列腺切除术（水消融手术）是一种越来越被认可的治疗有症状良性前列腺增生（BPH）的方法。我们在五个地点对178名男性进行了商业环境下水消融手术的安全性和有效性验证。平均前列腺体积为59立方厘米。手术时间平均为24分钟，总麻醉时长为50分钟。国际前列腺症状评分（IPSS）从基线时的21.6降至12个月随访时的6.5，改善了15.3分（<0.0001）。最大尿流率从基线时的10毫升/秒增加到第12个月时的20.8毫升/秒（增加了11.8毫升，<0.0001）。射精功能相对得以保留。经直肠超声评估的前列腺体积在术后三个月减少了36%。五名患者（2.7%）在术后第一周接受了输血。真实世界证据表明，水消融术治疗BPH安全有效。
