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个体安置与支持模式在诊断亚组、物质滥用和法医条件下的职业结果:系统评价和汇总原始数据的分析。

Vocational Outcomes of the Individual Placement and Support Model in Subgroups of Diagnoses, Substance Abuse, and Forensic Conditions: A Systematic Review and Analysis of Pooled Original Data.

机构信息

CORE: Copenhagen Research Center for Mental Health, Mental Health Centre Copenhagen, Gentofte Hospitalsvej 15, 2900, Hellerup, Denmark.

Department of Public Health, Aarhus University, Aarhus, Denmark.

出版信息

J Occup Rehabil. 2021 Dec;31(4):699-710. doi: 10.1007/s10926-021-09960-z. Epub 2021 Mar 4.

Abstract

PURPOSE

To investigate the effect of Individual Placement and Support (IPS) according to diagnoses of schizophrenia, bipolar disorder, major depression, substance use disorders, or forensic psychiatric conditions.

METHODS

A systematic search of the literature was conducted in June 2017 and repeated in December 2020. The systematic review included 13 studies. Analyses of pooled original data were based on the six studies providing data (n = 1594). No studies on forensic psychiatric conditions were eligible. Hours and weeks worked were analyzed using linear regression. Employment, and time to employment was analyzed using logistic regression, and cox-regression, respectively.

RESULTS

The effects on hours and weeks in employment after 18 months were comparable for participants with schizophrenia, and bipolar disorder but only statistically significant for participants with schizophrenia compared to services as usual (SAU) (EMD 109.1 h (95% CI 60.5-157.7), 6.1 weeks (95% CI 3.9-8.4)). The effect was also significant for participants with any drug use disorder (121.2 h (95% CI 23.6-218.7), 6.8 weeks (95% CI 1.8-11.8)). Participants with schizophrenia, bipolar disorder, and any drug use disorder had higher odds of being competitively employed (OR 2.1 (95% CI 1.6-2.7); 2.4 (95% CI 1.3-4.4); 3.0 (95% CI 1.5-5.8)) and returned to work faster than SAU (HR 2.1 (95% CI 1.6-2.6); 1.8 (95% CI 1.1-3.1); 3.0 (95% CI 1.6-5.7)). No statistically significant effects were found regarding depression.

CONCLUSIONS

IPS was effective regarding schizophrenia, bipolar disorder, and substance use disorder; however, the effect on hours, and weeks worked was not statistically significant regarding bipolar disorder. For people with depression the impact of IPS remains inconclusive. Non-significant results may be due to lack of power.

TRIAL REGISTRATION

PROSPERO protocol nr. CRD42017060524.

摘要

目的

根据精神分裂症、双相情感障碍、重性抑郁障碍、物质使用障碍或法医精神病状况的诊断,研究个体安置和支持(IPS)的效果。

方法

于 2017 年 6 月进行了文献系统检索,并于 2020 年 12 月重复检索。该系统综述共纳入 13 项研究。对提供数据的 6 项研究(n=1594)进行了汇总原始数据分析。没有符合法医精神病状况的研究合格。使用线性回归分析工作小时数和工作周数。使用逻辑回归和 Cox 回归分别分析就业情况和就业时间。

结果

18 个月后,IPS 对精神分裂症和双相情感障碍患者的就业时间和工作小时数的影响相当,但与常规服务(SAU)相比,仅对精神分裂症患者具有统计学意义(EMD 109.1 小时(95%CI 60.5-157.7),6.1 周(95%CI 3.9-8.4))。对于任何药物使用障碍的参与者,效果也很显著(121.2 小时(95%CI 23.6-218.7),6.8 周(95%CI 1.8-11.8))。精神分裂症、双相情感障碍和任何药物使用障碍患者的竞争就业的可能性更高(OR 2.1(95%CI 1.6-2.7);2.4(95%CI 1.3-4.4);3.0(95%CI 1.5-5.8)),并且比 SAU 更快地重返工作岗位(HR 2.1(95%CI 1.6-2.6);1.8(95%CI 1.1-3.1);3.0(95%CI 1.6-5.7))。关于抑郁,没有发现统计学意义上的效果。

结论

IPS 对精神分裂症、双相情感障碍和物质使用障碍有效;但是,对于双相情感障碍,对工作小时数和工作周数的影响没有统计学意义。对于抑郁症患者,IPS 的影响仍不确定。非显著结果可能是由于缺乏效力。

试验注册

PROSPERO 方案编号 CRD42017060524。

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