Department of Psychiatry, American University of Beirut Medical Center, Beirut, Lebanon.
Faculty of Medicine, American University of Beirut, Beirut, Lebanon.
BMJ Case Rep. 2021 Mar 4;14(3):e238957. doi: 10.1136/bcr-2020-238957.
Neurodegenerative and mood disorders in the geriatric population might exhibit interchangeable cognitive and behavioural symptoms. This overlap in presentation might raise a diagnostic challenge for psychiatrists evaluating elderly patients who are presenting with such symptoms. Additionally, there is limited data published about early psychiatric manifestations of neurodegenerative disorders in the elderly. We report a case of a 71-year-old with a history of refractory depressive disorder and multiple cardiovascular risk factors presenting with verbalisation of suicidal and homicidal intent as well as mixed mood and psychotic symptoms. The patient was diagnosed with Binswanger's disease (BD). We also provide a literature review of challenging early psychiatric presentations of neurocognitive disorders and a summary of similar cases to help facilitate diagnosis of BD cases in future.
老年人群中的神经退行性和情绪障碍可能表现出可互换的认知和行为症状。这种表现上的重叠可能会给评估出现此类症状的老年患者的精神科医生带来诊断上的挑战。此外,关于老年人神经退行性疾病的早期精神表现,发表的数据有限。我们报告了一例 71 岁的患者,有难治性抑郁症病史和多种心血管危险因素,表现出言语表达的自杀和杀人意图以及混合情绪和精神病症状。该患者被诊断为 Binswanger 病(BD)。我们还对神经认知障碍的早期具有挑战性的精神表现进行了文献回顾,并总结了类似病例,以帮助今后诊断 BD 病例。