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两阶段翻修术联合关节间切除术治疗人工关节置换术后感染的髋关节几何形状重建。

Restoration of the hip geometry after two-stage exchange with intermediate resection arthroplasty for periprosthetic joint infection.

机构信息

Department of Trauma Surgery, Orthopaedics and Plastic Surgery, University Medical Center Göttingen, Göttingen, Germany.

Department of Orthopaedics, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.

出版信息

Sci Rep. 2021 Mar 4;11(1):5221. doi: 10.1038/s41598-021-84692-x.

Abstract

Two-stage exchange with intermediate resection arthroplasty (RA) is a well-established surgical procedure in the treatment of chronic periprosthetic joint infection (PJI), whereby a higher failure rate of final hip geometry restoration due to tissue contraction is controversially discussed. The aim was to evaluate radiographic changes of hip geometry parameters during PJI treatment and to determine the impact of the intermediate RA on the final joint restoration after reimplantation of a total hip arthroplasty (reTHA). Radiographic parameters (leg length (LL), femoral offset (FO), horizontal/vertical acetabular center of rotation distance (h/vCORD)) of 47 patients (mean age: 64.1 years) were measured on standard radiographs of the pelvis and compared between four different stages during PJI treatment (pre-replacement status (preTHA), primary total hip arthroplasty (pTHA), RA and reTHA). The RA duration (mean: 10.9 months) and the number of reoperations during this period (mean: n = 2.0) as well as their impact on hip geometry restoration were evaluated. Between preTHA and pTHA/reTHA an equivalent restoration was measured regarding the FO (p < 0.001/p < 0.001) and hCORD (p = 0.016/p < 0.001), but not regarding the LL and vCORD. In contrast, analysis revealed no influence of RA and an equivalent reconstruction of LL (p = 0.003), FO (p < 0.001), v/hCORD (p = 0.039/p = 0.035) at reTHA compared to pTHA. Furthermore, RA duration (p = 0.053) and the number of reoperations after RA (p = 0.134) had no impact on radiographic hip geometry restoration. The two-stage exchange with intermediate RA does not alter the preexisting hip joint parameters, whereby a good restoration of the final hip geometry, independent of the duration or the number of reoperations, can be achieved.

摘要

两阶段翻修术结合中期关节切除成形术(RA)是治疗慢性假体周围关节感染(PJI)的一种成熟手术方法,但对于因组织收缩导致最终髋关节几何形状恢复失败率较高的问题存在争议。本研究旨在评估 PJI 治疗过程中髋关节几何参数的影像学变化,并确定 RA 对全髋关节置换术(reTHA)再植入后最终关节恢复的影响。对 47 例患者(平均年龄:64.1 岁)的骨盆标准 X 线片进行测量,并比较 PJI 治疗的四个不同阶段(置换前状态(preTHA)、初次全髋关节置换术(pTHA)、RA 和 reTHA)的影像学参数(下肢长度(LL)、股骨偏心距(FO)、水平/垂直髋臼旋转中心距离(h/vCORD))。评估 RA 持续时间(平均:10.9 个月)和在此期间的手术次数(平均:n = 2.0)及其对髋关节几何形状恢复的影响。在 preTHA 和 pTHA/reTHA 之间,FO(p < 0.001/p < 0.001)和 hCORD(p = 0.016/p < 0.001)的恢复等效,但 LL 和 vCORD 无差异。相比之下,分析显示 RA 无影响,在 reTHA 时与 pTHA 相比,LL(p = 0.003)、FO(p < 0.001)、v/hCORD(p = 0.039/p = 0.035)的重建等效。此外,RA 持续时间(p = 0.053)和 RA 后的手术次数(p = 0.134)对髋关节的影像学几何形状恢复无影响。两阶段翻修术结合中期 RA 不会改变现有的髋关节参数,从而可以实现最终髋关节几何形状的良好恢复,与 RA 持续时间或手术次数无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdda/7933341/0a0515414059/41598_2021_84692_Fig1_HTML.jpg

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