Department of Cardiovascular Surgery, German Aortic Centre Hamburg, University Heart & Vascular Centre Hamburg, Hamburg, Germany.
Department of Vascular Medicine, University Heart & Vascular Centre Hamburg, Hamburg, Germany.
Interact Cardiovasc Thorac Surg. 2021 Jun 28;33(1):85-92. doi: 10.1093/icvts/ivab059.
The goal of this study was to determine the outcome of patients undergoing an elective frozen elephant trunk (FET) procedure as a redo operation following previous cardiac surgery.
One hundred and eighteen consecutive patients underwent FET procedures between October 2010 and October 2019 at our centre. Patients were registered in a dedicated database and analysed retrospectively. Clinical and follow-up characteristics were compared between patients undergoing a FET operation as a primary (primary group) or a redo procedure (redo group) using logistic regression and Cox regression analysis. Emergency procedures (n = 33) were excluded from the analysis.
A total of 36.5% (n = 31) of the FET procedures were redo operations (redo group) and 63.5% (n = 54) of the patients underwent primary surgery (primary group). There was no significant difference in the 30-day mortality [primary group: 7.4%; redo group: 3.2%; 95% confidence interval (CI) (0.19-35.29); P = 0.63] and the 3-year mortality [primary group: 22.2%; redo group: 16.7%; 95% CI (0.23-3.23); P = 0.72] between redo and primary cases. Furthermore, the adjusted statistical analysis did not reveal significant differences between the groups in the occurrence of transient or permanent neurological deficit, paraplegia, acute renal failure and resternotomy. The redo group showed a higher rate of recurrent nerve palsy, which did not reach statistical significance [primary group: 3.7% (n = 2); redo group: 19.4% (n = 6); P = 0.091].
Elective FET procedures as redo operations performed by a dedicated aortic team following previous cardiac surgery demonstrate an adequate safety profile.
本研究旨在探讨先前接受过心脏手术的患者再次行择期体外循环下全主动脉弓置换术(frozen elephant trunk,FET)的结果。
本研究回顾性分析了 2010 年 10 月至 2019 年 10 月期间在我院行 FET 手术的 118 例连续患者的临床资料。患者的临床和随访特征使用逻辑回归和 Cox 回归分析进行比较。将 33 例急诊手术排除在分析之外。
共有 36.5%(n=31)的 FET 手术为再次手术(再次手术组),63.5%(n=54)的患者行初次手术(初次手术组)。两组间 30 天死亡率[初次手术组:7.4%(n=4);再次手术组:3.2%(n=1);95%置信区间(CI)(0.19-35.29);P=0.63]和 3 年死亡率[初次手术组:22.2%(n=13);再次手术组:16.7%(n=6);95% CI(0.23-3.23);P=0.72]差异均无统计学意义。此外,调整统计学分析后,两组间暂时性或永久性神经功能缺损、截瘫、急性肾衰竭和开胸的发生率差异均无统计学意义。再次手术组的膈神经损伤发生率较高,但差异无统计学意义[初次手术组:3.7%(n=2);再次手术组:19.4%(n=6);P=0.091]。
由专门的主动脉团队对先前接受过心脏手术的患者行择期 FET 手术作为再次手术是安全可行的。