Borrego-Jimenez Pedro-Santiago, Flores-Fraile Javier, Padilla-Fernández Bárbara-Yolanda, Valverde-Martinez Sebastián, Gómez-Prieto Agustín, Márquez-Sánchez Magaly Teresa, Mirón-Canelo José-Antonio, Lorenzo-Gómez María-Fernanda
Physiotherapy Department of Institute of Applied Technology, Abu Dhabi 3798, United Arab Emirates.
Department of Health Sciences and Education, University UDIMA, 28400 Madrid, Spain.
J Clin Med. 2021 Feb 19;10(4):862. doi: 10.3390/jcm10040862.
To prove the benefits of pelvic floor muscle training with biofeedback (BFB) as a complementary treatment in women with bladder pain syndrome/interstitial cystitis (BPS/IC).
Prospective, randomized study in 123 women with BPS/IC. Groups: BFB+ (n = 48): women with oral drug treatment (perphenazine and amitriptyline) plus intravesical instillations (sodium hyaluronate) plus pelvic floor muscle training with BFB; BFB-: (n = 75): women with oral drug treatment plus intravesical instillations.
age, body mass index (BMI), time of follow-up, length of disease, time free of disease, diseases and health conditions concomitant, and responses to the SF-36 health-related quality of life questionnaire at the first consultation (SF-36 pre-treatment), and at the end of the study (SF-36 post-treatment). The treatment was considered successful when the SF-36 score reached values equal to or greater than 80 points or when the initial value increased by 30 or more points.
Mean age was 51.62 years old (23-82). BMI was higher in BFB-. The mean length of BPS/IC condition was 4.92 years (1-20), shorter in BFB+ than in BFB-. Mean SF-36 score pre-treatment was 45.92 points (40-58), lower in BFB+ than in BFB-. Post-treatment SF-36 score was higher than pre-treatment SF-36 score both in BFB+ and BFB-. SF-36 values were higher in BFB+ compared to BFB- over the follow-up.
BFB improves quality of life in women with BPS/IC as adjunct therapy to combined oral and intravesical treatment.
证明盆底肌生物反馈训练（BFB）作为膀胱疼痛综合征/间质性膀胱炎（BPS/IC）女性辅助治疗方法的益处。
对123例BPS/IC女性进行前瞻性随机研究。分组：BFB+组（n = 48）：接受口服药物治疗（奋乃静和阿米替林）加膀胱内灌注（透明质酸钠）加盆底肌生物反馈训练的女性；BFB-组（n = 75）：接受口服药物治疗加膀胱内灌注的女性。
年龄、体重指数（BMI）、随访时间、病程、无病时间、伴随疾病和健康状况，以及首次咨询时（SF-36治疗前）和研究结束时（SF-36治疗后）对SF-36健康相关生活质量问卷的回答。当SF-36评分达到或高于80分，或初始值增加30分及以上时，治疗被认为成功。
平均年龄为51.62岁（23 - 82岁）。BFB-组的BMI较高。BPS/IC病程的平均时长为4.92年（1 - 20年），BFB+组比BFB-组短。治疗前SF-36平均评分为45.92分（40 - 58分），BFB+组低于BFB-组。BFB+组和BFB-组治疗后的SF-36评分均高于治疗前。在随访期间，BFB+组的SF-36值高于BFB-组。
作为口服和膀胱内联合治疗的辅助疗法，BFB可改善BPS/IC女性的生活质量。
