Institute of Nutrition, Mahidol University, Salaya, Phuttamonthon, Nakhon Pathom 73170, Thailand.
Food and Nutrition Academic and Research Cluster, Institute of Nutrition, Mahidol University, Salaya, Phuttamonthon, Nakhon Pathom 73170, Thailand.
Molecules. 2021 Feb 18;26(4):1082. doi: 10.3390/molecules26041082.
Craib. is an indigenous edible plant that became an endangered species due to limited consumption of the local population with unknown reproduction and growth conditions. The plant is used as a traditional herb; however, its health applications lack scientific-based evidence. Craib. plant parts (old leaves and young shoots) from four areas as Kamphaeng Phet (KP), Muang Nakhon Ratchasima (MN), Pakchong Nakhon Ratchasima (PN), and Uthai Thani (UT) origins were investigated for phenolic compositions and in vitro health properties through the inhibition of key enzymes relevant to obesity (lipase), diabetes (α-glucosidase and dipeptidyl peptidase-IV), Alzheimer's disease (cholinesterases and β-secretase), and hypertension (angiotensin-converting enzyme). Phenolics including -coumaric acid, sinapic acid, naringenin, and apigenin were detected in old leaves and young shoots in all plant origins. Old leaves exhibited higher total phenolic contents (TPCs) and total flavonoid contents (TFCs), leading to higher enzyme inhibitory activities than young shoots. Besides, PN and MN with higher TPCs and TFCs tended to exhibit greater enzyme inhibitory activities than others. These results will be useful to promote this plant as a healthy food with valuable medicinal capacities to support its consumption and agricultural stimulation, leading to sustainable conservation of this endangered species.
野生刺芹是一种土生土长的可食用植物，由于当地居民的食用量有限，且其繁殖和生长条件未知，该物种已濒临灭绝。这种植物被用作传统草药；然而，其对健康的应用缺乏基于科学的证据。对来自四个地区的野生刺芹植物部分（老叶和嫩枝）进行了研究，这些地区包括北标府（KP）、那空叻差是玛哈沙拉堪府（MN）、巴冲府（PN）和乌泰他尼府（UT），以通过抑制与肥胖（脂肪酶）、糖尿病（α-葡萄糖苷酶和二肽基肽酶-IV）、阿尔茨海默病（胆碱酯酶和β-分泌酶）和高血压（血管紧张素转化酶）相关的关键酶来研究其酚类成分和体外健康特性。在所有植物来源的老叶和嫩枝中都检测到了对香豆酸、芥子酸、柚皮素和芹菜素等酚类物质。老叶的总酚含量（TPCs）和总类黄酮含量（TFCs）较高，其对各种酶的抑制活性也高于嫩枝。此外，PN 和 MN 由于具有较高的 TPCs 和 TFCs，其对各种酶的抑制活性也高于其他地区。这些结果将有助于推广这种植物作为一种具有药用价值的健康食品，以支持其消费和农业刺激，从而实现对这种濒危物种的可持续保护。
