Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, UT 84132, USA.
Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT 84132, USA.
Med Sci (Basel). 2021 Feb 14;9(1):10. doi: 10.3390/medsci9010010.
Traumatic brain injury (TBI) is a widespread and expensive problem globally. The standard diagnostic workup for new TBI includes obtaining a noncontrast computed tomography image of the head, which provides quick information on operative pathologies. However, given the limited sensitivity of computed tomography for identifying subtle but meaningful changes in the brain, magnetic resonance imaging (MRI) has shown better utility for ongoing management and prognostication after TBI. In recent years, advanced applications of MRI have been further studied and are being implemented as clinical tools to help guide care. These include functional MRI, diffusion tensor imaging, MR perfusion, and MR spectroscopy. In this review, we discuss the scientific basis of each of the above techniques, the literature supporting their use in TBI, and how they may be clinically implemented to improve the care of TBI patients.
创伤性脑损伤(TBI)是一个在全球范围内广泛存在且代价高昂的问题。新的 TBI 的标准诊断包括获取头部的非对比计算机断层扫描图像,这可以快速提供手术病理学信息。然而,鉴于计算机断层扫描对识别大脑中细微但有意义的变化的有限敏感性,磁共振成像(MRI)已显示出在 TBI 后进行持续管理和预后方面具有更好的应用价值。近年来,MRI 的高级应用已进一步研究,并作为临床工具实施,以帮助指导护理。这些包括功能磁共振成像、扩散张量成像、磁共振灌注和磁共振波谱。在这篇综述中,我们讨论了上述每种技术的科学基础、支持其在 TBI 中应用的文献以及如何在临床上实施这些技术以改善 TBI 患者的护理。