Paixão Gustavo, Fontela Sofia Botelho, Marques Jorge, Esteves Alexandra, Charneca Rui, Payan-Carreira Rita
Animal and Veterinary Research Centre (CECAV), Universidade de Trás-os-Montes e Alto Douro, 5000-801 Vila Real, Portugal.
MED-Mediterranean Institute for Agriculture, Environment and Development & Dept. de Medicina Veterinária, Universidade de Évora | Pólo da Mitra, 7002-554 Évora, Portugal.
Animals (Basel). 2021 Feb 27;11(3):632. doi: 10.3390/ani11030632.
This study aimed to find a suitable immunocastration protocol for male Bísaro pigs (BP) due to the breed and production system particularities. Twenty-five male BP were treated with Improvac according to three protocols: using two (GrpE2 and L2) or three vaccinations (GrpL3) and starting at 9 (GrpE2) or 13 weeks old (GrpL2 and L3). Eleven animals were kept as intact males (GrpC). Scrotal measurements and the morphometry of the testes and epididymides collected at slaughter were used to survey the effectiveness of the immunocastration compared with the age-matched intact controls. Animals in groups E2 and L3 were kept until 57 weeks, after a second vaccination cycle at 49 and 53 weeks of age. Scrotal dimensions decreased to almost initial values in treated animals until 17 (GrpE2) and 21 weeks (GrpL2 and L3), thereafter increasing to post-pubertal values until around 29 or 37 weeks of age for groups E2 and L2, respectively, but only at 41 weeks in group L3. Between 41 and 49 weeks, scrotal dimensions were similar in treated and control animals, decreasing to the predicted pre-puberty size after the second cycle of vaccination. This study suggests the most suited protocol for males slaughtered at older ages includes three administrations of Improvac starting at 3 months of age, followed by a second vaccination cycle.
由于品种和生产系统的特殊性，本研究旨在为雄性比萨罗猪（BP）找到合适的免疫去势方案。25头雄性BP按照三种方案用英帕瓦克进行处理：采用两次（E2组和L2组）或三次疫苗接种（L3组），分别在9周龄（E2组）或13周龄（L2组和L3组）开始。11头动物作为未去势雄性饲养（C组）。与年龄匹配的未去势对照相比，通过屠宰时收集的阴囊测量以及睾丸和附睾的形态测量来评估免疫去势的效果。E2组和L3组的动物在49周和53周龄进行第二次疫苗接种周期后，饲养至57周。处理过的动物阴囊尺寸在17周（E2组）和21周（L2组和L3组）前降至几乎初始值，此后分别在E2组和L2组约29周或37周龄时增加至青春期后的值，但L3组仅在41周时增加。在41至49周之间，处理过的动物和对照动物的阴囊尺寸相似，在第二次疫苗接种周期后降至预测的青春期前大小。本研究表明，对于老龄屠宰的雄性猪，最适合的方案是从3月龄开始进行三次英帕瓦克接种，随后进行第二次疫苗接种周期。
