Cazzato Gerardo, Sergi Maria Chiara, Sablone Sara, Colagrande Anna, Lettini Teresa, Fanelli Francesco, Orsini Umberto, Ingravallo Giuseppe
Section of Pathology, Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, 70124 Bari, Italy.
Section of Medical Oncology, Department of Biomedical Sciences and Clinical Oncology (DIMO), University of Bari Aldo Moro, 70124 Bari, Italy.
Dermatopathology (Basel). 2021 Feb 27;8(1):40-44. doi: 10.3390/dermatopathology8010008.
Leiomyosarcoma is a malignant smooth muscle neoplasm, which is traditionally divided into superficial and deep tumors. Superficial leiomyosarcomas are quite rare entities, accounting for approximately 7% of soft tissue neoplasms and 0.04% of all cancers. Here we describe a rare case of advanced primary cutaneous leiomyosarcoma (PCL) in a 93-year-old woman, highlighting the considerable size of the lesion and the correct surgical and oncological management. The clinical story began about 4 years ago, and the neoplasia was treated only with local radiotherapy, but the patient suffered from a dramatic volumetric increase of the right arm sarcoma one year ago. Then, an amputation of the limb was performed without following adjuvant chemotherapy. Currently, she does not show signs of recurrence and is in good shape.
平滑肌肉瘤是一种恶性平滑肌肿瘤，传统上分为浅表性和深部肿瘤。浅表性平滑肌肉瘤是相当罕见的实体，约占软组织肿瘤的7%，占所有癌症的0.04%。在此，我们描述了一例93岁女性晚期原发性皮肤平滑肌肉瘤（PCL）的罕见病例，强调了病变的相当大尺寸以及正确的手术和肿瘤学管理。临床情况始于约4年前，该肿瘤仅接受了局部放疗，但患者一年前右臂肉瘤体积急剧增大。然后，未进行辅助化疗就进行了肢体截肢。目前，她没有复发迹象，身体状况良好。
