Feng Xiaofen, Nan Yan, Pan Jiandong, Zou Ruitao, Shen Lijun, Chen Feng
School of Ophthalmology & Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Ruian Maternity and Child Care Hospital, Wenzhou, Zhejiang, China.
BMC Ophthalmol. 2021 Mar 6;21(1):120. doi: 10.1186/s12886-021-01833-6.
To study optic disc features of premature infants and compare to that of term infants to explore the pattern and features of newborn optic disc development and provide the basis for the diagnosis of newborn optic disc disease.
This was a prospective clinical research. Newborns underwent newborn fundus disease screening from January 1st, 2016 to October 31st, 2016 in the neonatal ward of Ruian City Maternal and Child Health Hospital were selected. RetCam 3 Version6.1.25.0 Wide-Field Digital Pediatric Retinal Imaging System developed by Clarity Medical Systems, Inc was adopted to conduct fundus examination on both eyes, 130 degree wide-angle lens was used to film the images centering optic disc.
For both premature infants and full-term newborns, vertical diameter of the optic disc to lateral diameter of the optic disc ratio was > 1, and the shape of the optic disc was a vertical oval. The difference of each optic disc parameter between premature infants and full-term newborns was not statistically significant (P > 0.05). There's a difference of constitution of sclerotic ring type on optic disc between premature infants and full-term newborns. Among which, the proportion of single ring type and double ring type in premature infants was higher than that in full-term newborns (P < 0.05). The proportion of no ring type in full-term newborns was higher than that in premature infants (P < 0.05). The proportion of mixed type had no significant difference (P > 0.05) between premature infants and full-term newborns.
We found that The proportion of mature types (single ring type and double ring type) in full-term newborns was higher than that in premature infants. While there's no statistical difference of the proportion of mixed types between premature infants and full-term newborns. Double ring type was a normal stage of the development of optic disc.
研究早产儿视盘特征并与足月儿进行比较，以探索新生儿视盘发育的规律和特点，为新生儿视盘疾病的诊断提供依据。
这是一项前瞻性临床研究。选取2016年1月1日至2016年10月31日在瑞安市妇幼保健院新生儿病房接受新生儿眼底疾病筛查的新生儿。采用Clarity Medical Systems公司研发的RetCam 3 Version6.1.25.0广角数字小儿视网膜成像系统对双眼进行眼底检查，使用130度广角镜头以视盘为中心拍摄图像。
早产儿和足月儿的视盘垂直径与横径之比均>1，视盘形状为垂直椭圆形。早产儿和足月儿各视盘参数差异无统计学意义（P>0.05）。早产儿和足月儿视盘巩膜环类型构成存在差异。其中，早产儿单环型和双环型的比例高于足月儿（P<0.05）。足月儿无环型的比例高于早产儿（P<0.05）。早产儿和足月儿混合型的比例差异无统计学意义（P>0.05）。
我们发现足月儿成熟型（单环型和双环型）的比例高于早产儿。而早产儿和足月儿混合型的比例无统计学差异。双环型是视盘发育的一个正常阶段。
