Lao Ji-Meng, Li Chu-Lan, Chen Yi-Jing, Mao Jian-Bo, Shen Li-Jun
Department of Ophthalmology, Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou 310000, Zhejiang Province, China.
Department of Ophthalmology, the Second People's Hospital of Foshan, Foshan 528000, Guangzhou Province, China.
Int J Ophthalmol. 2025 Mar 18;18(3):404-408. doi: 10.18240/ijo.2025.03.05. eCollection 2025.
To compare the cup-to-disc ratio (CDR) and optic disc morphology between eyes with congenital cataract and eyes without cataract in children under 3 years old.
This study included 63 patients with bilateral congenital cataract (mean age of 55.72±46.50wk, 44 were male), 33 patients with unilateral cataract (mean age of 56.63±33.23wk, 16 were male), and 31 age-matched healthy children (mean age of 55.80±29.29wk, 17 were male). Fundus photographs were taken with the RetCam 3 system. The horizontal-to-vertical disc diameter ratio (HVDR) was used as an index to describe the oval form of the optic disc.
The horizontal cup-to-disc ratio (HCDR), vertical cup-to-disc ratio (VCDR) and HVDR of cataract eyes in unilateral groups were significantly smaller than those of the normal eyes (<0.05). In the unilateral group, the HCDR, VCDR and HVDR of cataract eyes were significantly smaller than those in fellow eyes (<0.05). The HVDR of eyes in the bilateral group was significantly smaller than those in the age-matched normal eyes (<0.001). The form of optic disc of the cataract eyes in both the bilateral and unilateral groups was more vertical-oral than the normal eyes in the unilateral and the age-matched groups (<0.05).
Our results show that eyes with congenital cataract has a smaller HVDR and the form of the optic disc tended to be vertical-oval in young children.
比较3岁以下儿童先天性白内障患眼与无白内障患眼的杯盘比（CDR）及视盘形态。
本研究纳入63例双侧先天性白内障患者（平均年龄55.72±46.50周，男性44例）、33例单侧白内障患者（平均年龄56.63±33.23周，男性16例）以及31例年龄匹配的健康儿童（平均年龄55.80±29.29周，男性17例）。使用RetCam 3系统拍摄眼底照片。采用水平与垂直视盘直径比（HVDR）作为描述视盘椭圆形形态的指标。
单侧组白内障患眼的水平杯盘比（HCDR）、垂直杯盘比（VCDR）及HVDR均显著小于正常眼（<0.05）。在单侧组中，白内障患眼的HCDR、VCDR及HVDR均显著小于对侧眼（<0.05）。双侧组患眼的HVDR显著小于年龄匹配的正常眼（<0.001）。双侧组和单侧组白内障患眼的视盘形态比单侧组正常眼及年龄匹配组正常眼更呈垂直-椭圆形（<0.05）。
我们的结果表明，先天性白内障患眼的HVDR较小，且幼儿视盘形态倾向于垂直椭圆形。
