Conte B, D'Aranno V, Santicioli P, Giuliani S, Mancinelli A, Furio M, Maggi C A, Meli A
Pharmacology Department, Menarini Sud, Rome, Italy.
J Pharmacol Methods. 1988 Mar;19(1):57-61. doi: 10.1016/0160-5402(88)90045-9.
A new cystometric technique has been developed that is suitable for quantitative studies on physiopharmacology of micturition in conscious, freely moving rats. The method involves the transvesical infusion of warm saline at various filling rates through a catheter chronically implanted into the bladder dome. The various parameters of the collecting and voiding phase of the cystometrogram were recorded. Results obtained indicate that characteristics of the bladder voiding cycle of conscious, freely moving rats are qualitatively similar but quantitatively different from those described previously in anesthetized animals.
一种新的膀胱内压测量技术已经被开发出来，它适用于对清醒、自由活动大鼠排尿生理药理学的定量研究。该方法包括通过长期植入膀胱顶部的导管以不同的充盈速率经膀胱灌注温盐水。记录膀胱内压图收集和排尿阶段的各种参数。所得结果表明，清醒、自由活动大鼠膀胱排尿周期的特征在定性上相似，但在定量上与先前在麻醉动物中描述的不同。
