Higgins C B, Holt W, Pflugfelder P, Sechtem U
Department of Radiology, University of California Medical Center, San Francisco 94143.
Magn Reson Med. 1988 Feb;6(2):121-39. doi: 10.1002/mrm.1910060202.
This review examines the capability of cine MRI for evaluation of cardiovascular function and shows early results in valvular, ischemic, and congenital heart disease. MR assessment of left and right ventricular volumes is independent of geometrical models; dimensional values have been defined for normal individuals. Noninvasive measurement of peak and end systolic pressure along with cine MR imaging can be used to calculate left ventricular meridional wall stress which can be used for monitoring of myocardial diseases and evaluation of therapeutic intervention. Cine MR may be more accurate than angiography for identifying regional LV dysfunction since it can measure wall thickening as well as inward wall motion. Regurgitant jets due to valvular lesions are readily seen and their characteristics may be used to define the severity of aortic or mitral regurgitation. Calculation of the regurgitant volume separates patients with mild, moderate, or severe disease. Likewise, the shunt flow across ventricular and atrial septal defects has been visualized in cine MR images and shunt flow calculated. Cine MRI serves as a three-dimensional imaging technique with high temporal resolution. It extends the capability of MRI in cardiac disease beyond the depiction of anatomy and renders a comprehensive cardiac imaging technique for quantitation of cardiac anatomy and function.
本综述探讨了电影磁共振成像（cine MRI）评估心血管功能的能力，并展示了其在瓣膜性、缺血性和先天性心脏病方面的早期研究结果。磁共振成像（MR）对左、右心室容积的评估不依赖于几何模型；已为正常个体定义了相关维度值。结合电影磁共振成像，对收缩压峰值和末期压力进行无创测量，可用于计算左心室子午线壁应力，进而用于监测心肌疾病和评估治疗干预效果。电影磁共振成像在识别局部左心室功能障碍方面可能比血管造影更准确，因为它既能测量室壁增厚，又能测量室壁内向运动。瓣膜病变导致的反流束很容易被观察到，其特征可用于确定主动脉瓣或二尖瓣反流的严重程度。通过计算反流容积可区分轻度、中度或重度疾病患者。同样，电影磁共振成像（cine MR）图像中已能显示室间隔和房间隔缺损处的分流情况，并可计算分流量。电影磁共振成像作为一种具有高时间分辨率的三维成像技术，拓展了磁共振成像在心脏病领域的应用能力，使其不仅仅局限于解剖结构的描绘，而是成为一种用于定量心脏解剖结构和功能的全面心脏成像技术。
