Arafat Yara, Mohamed Ibrahim Mohamed Izham, Awaisu Ahmed, Owusu Yaw
Clinical Pharmacy and Practice Department, College of Pharmacy, QU Health, Qatar University, Doha, Qatar.
J Pharm Bioallied Sci. 2020 Oct-Dec;12(4):400-405. doi: 10.4103/jpbs.JPBS_156_20. Epub 2020 Oct 8.
Advanced stages of change (SOC) are usually associated with lower glycated hemoglobin (HbA1c) scores in patients with type 2 diabetes mellitus (T2DM). Additionally, these patients' adherence to antidiabetic medications is crucial to achieve controlled HbA1c scores. The purpose of this study was to determine the relationship between SOC and HbA1c as well as between medication adherence and HbA1c in patients with T2DM in a primary health-care setting in Qatar.
A cross-sectional observational study was conducted in patients with T2DM at the noncommunicable diseases clinics at Mesaimeer Healthcare Center and West Bay Health Care Center. Medication adherence was assessed using the Morisky Medication Adherence Scale (MMAS-8), whereas a two-item SOC questionnaire was used to measure the SOC. HbA1c values were obtained from the electronic database at the clinic. Spearman rank correlations were performed, with the significance level set at α < 0.05.
A total of 387 patients were included in the analysis. More than 75% of them reported that they were in the maintenance stage, and 35.4% of them had a controlled diabetes status. There was no significant correlation between SOC and HbA1c or between medication adherence and HbA1c.
There was no relationship between SOC and HbA1c or between medication adherence and HbA1c in patients with T2DM, indicating that in this study, self-reported measures are not associated with the HbA1c scores of patients.
在2型糖尿病(T2DM)患者中,行为改变的高级阶段(SOC)通常与较低的糖化血红蛋白(HbA1c)得分相关。此外,这些患者对抗糖尿病药物的依从性对于实现HbA1c得分的控制至关重要。本研究的目的是确定卡塔尔初级卫生保健机构中T2DM患者的SOC与HbA1c之间以及药物依从性与HbA1c之间的关系。
在迈赛米尔医疗中心和西湾医疗中心的非传染性疾病诊所对T2DM患者进行了一项横断面观察性研究。使用Morisky药物依从性量表(MMAS-8)评估药物依从性,而使用一个两项的SOC问卷来测量SOC。HbA1c值从诊所的电子数据库中获取。进行Spearman等级相关性分析,显著性水平设定为α<0.05。
共有387名患者纳入分析。超过75%的患者报告他们处于维持阶段,其中35.4%的患者糖尿病病情得到控制。SOC与HbA1c之间或药物依从性与HbA1c之间均无显著相关性。
T2DM患者的SOC与HbA1c之间以及药物依从性与HbA1c之间均无关系,这表明在本研究中,自我报告的指标与患者的HbA1c得分无关。