Alshablan Abdullah, Jabbad Reem, Tayeb Sarah, Albeshri Tariq, Yelamanchili Suvarna Raju, Rabie Nada, Almutairi Fahdah, Samannodi Mohammed
Department of Medicine, King Fahad Armed Forces Hospital, Jeddah, Saudi Arabia.
Department of Pharmacy, King Fahad Armed Forces Hospital, Jeddah, Saudi Arabia.
Clin Med Insights Case Rep. 2021 Feb 19;14:1179547621996306. doi: 10.1177/1179547621996306. eCollection 2021.
Adult Still's disease (ASD) is an uncommon inflammatory disorder characterized by fevers, a salmon-colored rash, and arthritis. Cytokines storm syndrome related to Coronavirus-19 (COVID-19) usually occur in acute period of COVID-19 and can mimic clinical features of ASD.
We present a case of a 27-year-old male who was hospitalized in July 2020 due to fever, sore throat, multiple joint pain, and body rash for 2 weeks. Patient recovered from COVID-19 8 weeks ago but his nasopharyngeal SARS CoV-2 PCR was still positive on current hospitalization. Post COVID-19 cytokines storm syndrome post COVID-19 was suspected but after further assessment and investigations, diagnosis of ASD was established and patient was treated with corticosteroids therapy and had favorable outcome.
During COVID-19 pandemic, diagnosis of many other diseases either were delayed or missed. We encourage all clinicians to have a broader differential diagnosis to improve patient care and outcome.
成人斯蒂尔病(ASD)是一种罕见的炎症性疾病,其特征为发热、鲑鱼色皮疹和关节炎。与冠状病毒病-19(COVID-19)相关的细胞因子风暴综合征通常发生在COVID-19的急性期,可模拟ASD的临床特征。
我们报告一例27岁男性病例,该患者于2020年7月因发热、咽痛、多关节疼痛和皮疹入院,症状持续2周。患者8周前从COVID-19中康复,但此次住院时鼻咽部严重急性呼吸综合征冠状病毒2(SARS-CoV-2)聚合酶链反应(PCR)检测仍为阳性。怀疑该患者患有COVID-19后细胞因子风暴综合征,但经过进一步评估和检查,确诊为ASD,并给予患者皮质类固醇治疗,结果良好。
在COVID-19大流行期间,许多其他疾病的诊断被延迟或漏诊。我们鼓励所有临床医生进行更广泛的鉴别诊断,以改善患者护理和治疗结果。