Haematopoiesis and Leukocyte Biology, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Department of Diabetes, Monash University, Melbourne, VIC, Australia.
Front Endocrinol (Lausanne). 2021 Feb 19;11:620466. doi: 10.3389/fendo.2020.620466. eCollection 2020.
Over the past decade, the use of probiotics to modify the gut microbiome has become a public spotlight in reducing the severity of a number of chronic diseases such as autoimmune disease, diabetes, cancer and cardiovascular disease. Recently, the gut microbiome has been shown to play an important role in regulating bone mass. Therefore, targeting the gut microbiome may be a potential alternative avenue for those with osteopenia or osteoporosis. In this mini-review, we take the opportunity to delve into how the different components of the gut work together and how the gut-related diseases impact on bone health.
在过去的十年中，益生菌被广泛用于调节肠道微生物组，以减轻多种慢性疾病（如自身免疫性疾病、糖尿病、癌症和心血管疾病）的严重程度。最近，肠道微生物组在调节骨量方面的作用已得到证实。因此，针对肠道微生物组可能是治疗骨质疏松症或骨量减少症的一种潜在替代途径。在这篇小型综述中，我们将探讨肠道的不同组成部分如何协同作用，以及肠道相关疾病如何影响骨骼健康。
