Hedayati Mohammad-Taghi, Montazeri Mahdi, Rashidi Negin, Yousefi-Abdolmaleki Elham, Shafiee Mohammad-Ali, Maleki Ali, Farmani Maryam, Montazeri Mohammad
Department of Cardiology, Babol University of Medical Sciences, Babol, Iran.
Division of General Internal Medicine, Department of Medicine, Toronto General Hospital, Toronto, Canada.
Caspian J Intern Med. 2021 Winter;12(1):59-64. doi: 10.22088/cjim.12.1.59.
White blood cell count (WBC) is one of the objective parameters of systemic inflammation. The aim of present study was to evaluate the relationship between WBC count and metabolic syndrome.
In this study on Lor population in Borujerd province (West of Iran), from 2011 to 2013, 800 persons were enrolled. MetS was defined based on ATP III criteria. Differences among the quartiles of WBC were examined by one-way analysis of variance.
Only 14.7% did not have any of the five components and 43% of all subjects had metabolic syndrome. The means of WBC count in MetS group were significantly higher than the control group (p<0.0001). In subjects without any MetS components, the means of WBC was 5.321 /µL, and it was 5.664, 5.714, 5.961, 6.302, and 6.572 /µL in subjects with 1, 2, 3, 4, and 5 components, respectively. These differences show a significant increasing trend (p<0.0001).
WBC count was associated with clustered components of metabolic syndrome. It seems that WBC counts could be considered as a predictive factor for metabolic syndrome in preventive medicine.
白细胞计数(WBC)是全身炎症的客观参数之一。本研究的目的是评估白细胞计数与代谢综合征之间的关系。
在这项针对伊朗西部博鲁杰尔德省洛尔人群的研究中,2011年至2013年共纳入800人。代谢综合征根据ATP III标准定义。通过单因素方差分析检验白细胞四分位数之间的差异。
只有14.7%的人没有这五种成分中的任何一种,所有受试者中有43%患有代谢综合征。代谢综合征组的白细胞计数平均值显著高于对照组(p<0.0001)。在没有任何代谢综合征成分的受试者中,白细胞平均值为5.321/µL,在有1、2、3、4和5种成分的受试者中,白细胞平均值分别为5.664、5.714、5.961、6.302和6.572/µL。这些差异呈现出显著的上升趋势(p<0.0001)。
白细胞计数与代谢综合征的聚集成分相关。在预防医学中,白细胞计数似乎可被视为代谢综合征的一个预测因素。