Al Rajeh S, Awada A, Naufal R, Amene P, Larbi E, Obeid T
Division of Neurology, King Fahad National Guard Hospital, Riyadh, Saudi Arabia.
J Neurol Sci. 1995 Dec;134(1-2):167-70. doi: 10.1016/0022-510x(95)00239-5.
The angiographic findings in 100 Saudi patients with carotid ischemic cerebrovascular disease (CVD) (transient ischemic attacks (TIA) or strokes) were retrospectively reviewed. These patients were representative of all patients with similar disorders in the terms of sex, frequency of diabetes mellitus and ischemic heart disease. They were, however, significantly younger, smoked more, had more cervical bruits and less atrial fibrillation. Analysis of the data showed that a significant stenosis (> 70%) of the carotid artery origin was found only in 12% of TIA cases, 4% in the lacunar infarction cases and 6% of the large infarction cases on the symptomatic side and only in one case of TIA in the asymptomatic side. These frequencies were significantly lower than those found in similar studies performed in western countries. This study suggests that stenoses and occlusions of extracranial carotid artery plays a smaller role in the pathogenesis of ischemic CVD in Saudis than in Caucasians. The low consumption of cigarettes among elderly and females may be one of the explanations.
对100例沙特阿拉伯颈动脉缺血性脑血管疾病（CVD）（短暂性脑缺血发作（TIA）或中风）患者的血管造影结果进行了回顾性研究。就性别、糖尿病和缺血性心脏病的发病率而言，这些患者代表了所有患有类似疾病的患者。然而，他们明显更年轻，吸烟更多，颈部血管杂音更多，房颤更少。数据分析表明，仅在12%的TIA病例、4%的腔隙性梗死病例和6%的有症状侧大面积梗死病例中发现颈动脉起始处有明显狭窄（>70%），而在无症状侧仅在1例TIA病例中发现。这些频率显著低于在西方国家进行的类似研究中发现的频率。这项研究表明，颅外颈动脉狭窄和闭塞在沙特人缺血性CVD发病机制中的作用比在白种人中要小。老年人和女性吸烟率低可能是原因之一。
