Zhang Hanlin, Wang Yuanzhuo, Zheng Qingyue, Tang Keyun, Fang Rouyu, Wang Yuchen, Sun Qiuning
Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Front Oncol. 2021 Feb 18;11:629687. doi: 10.3389/fonc.2021.629687. eCollection 2021.
Melanoma is a severe skin cancer that metastasizes quickly. Bibliometric analysis can quantify hotspots of research interest. Google Trends can provide information to address public concerns.
The top 15 most frequently cited articles on melanoma each year from 2015 to 2019, according to annual citations, were retrieved from the Web of Science database. Original articles, reviews, and research letters were included in this research. For the Google Trends analysis, the topic "Melanoma" was selected as the keyword. Online search data from 2004 to 2019 were collected. Four countries (New Zealand, Australia, the United States and the United Kingdom) were selected for seasonal analysis. Annual trends in relative search volume and seasonal variation were analyzed, and the top related topics and rising related topics were also selected and analyzed.
The top 15 most frequently cited articles each year were all original articles that focused on immunotherapy (n=8), omics (n=5), and the microbiome (n=2). The average relative search volume remained relatively stable across the years. The seasonal variation analysis revealed that the peak appeared in summer, and the valley appeared in winter. The diseases associated with or manifestations of melanoma, treatment options, risk factors, diagnostic tools, and prognosis were the topics in which the public was most interested. Most of the topics revealed by bibliometric and Google Trends analyses were consistent, with the exception of issues related to the molecular biology of melanoma.
This study revealed the trends in research interest and public interest in melanoma, which may pave the way for further research.
黑色素瘤是一种严重的皮肤癌，转移迅速。文献计量分析可以量化研究热点。谷歌趋势可以提供信息以解决公众关注的问题。
从科学网数据库中检索出2015年至2019年每年被引用次数最多的关于黑色素瘤的15篇文章。本研究纳入原创文章、综述和研究快报。对于谷歌趋势分析，选择“黑色素瘤”这一主题作为关键词。收集2004年至2019年的在线搜索数据。选择四个国家（新西兰、澳大利亚、美国和英国）进行季节性分析。分析相对搜索量的年度趋势和季节性变化，并选择和分析最相关主题和新兴相关主题。
每年被引用次数最多的15篇文章均为原创文章，主要集中在免疫疗法（n = 8）、组学（n = 5）和微生物组（n = 2）。多年来平均相对搜索量保持相对稳定。季节性变化分析显示，高峰期出现在夏季，低谷期出现在冬季。与黑色素瘤相关或其表现、治疗选择、风险因素、诊断工具和预后等疾病是公众最感兴趣的主题。文献计量分析和谷歌趋势分析揭示的大多数主题是一致的，但黑色素瘤分子生物学相关问题除外。
本研究揭示了黑色素瘤的研究兴趣和公众兴趣趋势，这可能为进一步研究铺平道路。
