Xu Weize, Yu Kai, Ye Jingjing, Li Haomin, Chen Jiajia, Yin Fei, Xu Jingfang, Zhu Jihua, Li Die, Shu Qiang
Department of Cardiac Surgery, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, 310057 Hangzhou, China.
Department of Ultrasound, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, 310057 Hangzhou, China.
Artif Intell Med. 2022 Apr;126:102257. doi: 10.1016/j.artmed.2022.102257. Epub 2022 Feb 19.
Congenital heart diseases (CHD) are the most common birth defects, and the early diagnosis of CHD is crucial for CHD therapy. However, there are relatively few studies on intelligent auscultation for pediatric CHD, due to the fact that effective cooperation of the patient is required for the acquisition of useable heart sounds by electronic stethoscopes, yet the quality of heart sounds in pediatric is poor compared to adults due to the factors such as crying and breath sounds. This paper presents a novel pediatric CHD intelligent auscultation method based on electronic stethoscope. Firstly, a pediatric CHD heart sound database with a total of 941 PCG signal is established. Then a segment-based heart sound segmentation algorithm is proposed, which is based on PCG segment to achieve the segmentation of cardiac cycles, and therefore can reduce the influence of local noise to the global. Finally, the accurate classification of CHD is achieved using a majority voting classifier with Random Forest and Adaboost classifier based on 84 features containing time domain and frequency domain. Experimental results show that the performance of the proposed method is competitive, and the accuracy, sensitivity, specificity and f1-score of classification for CHD are 0.953, 0.946, 0.961 and 0.953 respectively.
先天性心脏病(CHD)是最常见的出生缺陷,CHD的早期诊断对其治疗至关重要。然而,针对小儿CHD的智能听诊研究相对较少,因为电子听诊器获取可用心音需要患者的有效配合,而由于哭闹和呼吸音等因素,小儿的心音质量与成人相比很差。本文提出了一种基于电子听诊器的新型小儿CHD智能听诊方法。首先,建立了一个包含941个心音图(PCG)信号的小儿CHD心音数据库。然后提出了一种基于段的心音分割算法,该算法基于PCG段实现心动周期的分割,从而可以减少局部噪声对全局的影响。最后,基于包含时域和频域的84个特征,使用随机森林和Adaboost分类器的多数投票分类器实现CHD的准确分类。实验结果表明,该方法的性能具有竞争力,CHD分类的准确率、灵敏度、特异性和F1分数分别为0.953、0.946、0.961和0.953。