IRCCS San Raffaele Scientific Institute, via Olgettina 60, Milan, Italy.
IRCCS San Raffaele Scientific Institute, via Olgettina 60, Milan, Italy, Vita-Salute San Raffaele University, Milan, Italy.
Acta Biomed. 2021 Feb 16;92(1):e2021166. doi: 10.23750/abm.v92i1.11155.
A potential correlation between severe acute respiratory syndrome coronavirus 2 and air pollution has been suggested in some nationwide studies. It is not clear whether air pollution contributes to the spread of SARS-CoV-2 and to increase mortality.
Data on COVID-19 incidence, mortality rate, air pollution, and greenhouse gas element of 33 European countries were extracted from public available databases and analysed with Pearson correlation analysis for the overall population and normalizing for the population over 65 years.
Air pollutant agents such as particulate matter <10µm (PM10), particulate matter <2.5µm (PM2.5), ammonia (NH3), sulphur dioxide (SO2), non-methane volatile organic compounds (NMVOCs), nitrogen dioxide (NO2) and greenhouse gas elements recorded showed a remarkable correlation with cumulative positive number of SARS-CoV-2 cases and with cumulative number of COVID-19 deaths. PM2.5 (r = 0.68, p-value = 0.0001 for cumulative positive cases; r = 0.73, p-value <0.0001 for cumulative deaths) and nitrogen oxides (r = 0.85, p-value <0.0001 for cumulative positive cases; r = 0.70, p-value 0.0001 for cumulative deaths) were among the pollutant agents with the strongest correlation for both positive cases and deaths.
High levels of pollution in European countries should be considered a potential risk for severe COVID-19 and SARS-CoV-2-related death.
一些全国性研究表明，严重急性呼吸综合征冠状病毒 2 与空气污染之间可能存在关联。目前尚不清楚空气污染是否会导致 SARS-CoV-2 的传播和死亡率的增加。
从公共数据库中提取了 33 个欧洲国家的 COVID-19 发病率、死亡率、空气污染和温室气体元素数据，并对所有人群进行了 Pearson 相关分析，并针对 65 岁以上人群进行了归一化分析。
空气污染物，如 10µm 以下颗粒物（PM10）、2.5µm 以下颗粒物（PM2.5）、氨（NH3）、二氧化硫（SO2）、非甲烷挥发性有机化合物（NMVOCs）、二氧化氮（NO2）和温室气体元素，与 SARS-CoV-2 累计阳性病例数和 COVID-19 累计死亡人数呈显著相关。PM2.5（r = 0.68，p 值= 0.0001，用于累计阳性病例；r = 0.73，p 值<0.0001，用于累计死亡）和氮氧化物（r = 0.85，p 值<0.0001，用于累计阳性病例；r = 0.70，p 值= 0.0001，用于累计死亡）是与阳性病例和死亡均具有最强相关性的污染物之一。
欧洲国家高水平的污染应被视为 COVID-19 严重和与 SARS-CoV-2 相关死亡的潜在风险。
