Department of Clinical Pharmacy, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, 530021, Guangxi, China.
Intravenous Admixture Services Centre, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, 530021, Guangxi, China.
Sci Rep. 2021 Mar 8;11(1):5445. doi: 10.1038/s41598-021-85077-w.
Centralized intravenous admixture service (CIVAS) centres, which are pharmaceutical departments found in Chinese hospitals, provide high-quality intravenous fluids and pharmaceutical services for patients, and errors in their working procedures can lead to adverse consequences. Pharmacists, the primary CIVAS centre personnel, play a role in risk control; however, to date, the effect of pharmacists' participation in risk management has not been reported. The main aim of this study was to evaluate the pharmacist's role in risk control and evaluate its impact. A retrospective observational study was designed to assess the principal working process in the CIVAS centre of a provincial healthcare setting. Errors in the main working process were identified, and intervention measures were formulated. The pharmacist intervention effect was evaluated by assessing the identification rate of improper prescriptions; the incidence rate of drug preparation, compounding, packaging and delivery process errors; and expenditures on wasteful drugs. There was a higher identification rate for improper prescriptions after the intervention (P < 0.05), while the incidence of drug preparation (P < 0.05), admixture (P < 0.05), and packaging and delivery errors (P < 0.01) was significantly lower; the total wasteful medication expenditure was also dramatically reduced. The potential creativity of pharmacists in error control can provide dependable intravenous drugs for patients and reduce the running expenditures for CIVAS.
静脉药物配置中心(CIVAS)是中国医院的药学部门,为患者提供高质量的静脉输液和药学服务,其工作流程中的错误可能导致不良后果。药师作为 CIVAS 中心的主要工作人员,在风险控制中发挥着作用;然而,迄今为止,药师参与风险管理的效果尚未得到报道。本研究旨在评估药师在风险控制中的作用,并评估其影响。采用回顾性观察研究设计,评估省级医疗机构 CIVAS 中心的主要工作流程。识别主要工作流程中的错误,并制定干预措施。通过评估不合格处方的识别率、药物准备、配制、包装和配送过程错误的发生率以及浪费药物的支出,评估药师干预的效果。干预后不合格处方的识别率更高(P<0.05),而药物准备(P<0.05)、混合(P<0.05)和包装及配送错误(P<0.01)的发生率显著降低;浪费药物的总支出也大大减少。药师在差错控制方面的潜在创造力可以为患者提供可靠的静脉药物,并降低 CIVAS 的运行成本。