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乳腺癌与职业暴露:文献综合综述

Breast cancer and occupational exposures: an integrative review of the literature.

作者信息

Brito-Marcelino Arthur, Duarte-Tavares Rodrigo Japur, Marcelino Katienne Brito, Silva-Neto Julio Alves

机构信息

Fonoaudiologia, Hospital de Urgência de Sergipe, Aracaju, SE, Brazil.

Fundação Oswaldo Cruz (Fiocruz), Rio de janeiro, RJ, Brazil.

出版信息

Rev Bras Med Trab. 2021 Mar 3;18(4):488-496. doi: 10.47626/1679-4435-2020-595.

Abstract

Occupational factors can lead to breast cancer, though the relationship between these variables is not well established. The objective of this study was to search the relevant literature for information on the association between breast cancer and exposure to occupational risk factors. For that purpose, electronic databases were searched using the following keywords: breast cancer and occupational exposures. A total of 40 articles published in the 10-year period from 2009 to 2019 were included in this review. Workers exposed to metals such as cadmium, chemical products, radiation and night work were more susceptible to breast cancer. The findings showed significant evidence to support an association between breast cancer and some chemical products, ionizing radiation and night work. However, most studies have difficulty establishing a causal relationship between these variables, pointing to the need for further investigation of these issues.

摘要

职业因素可能导致乳腺癌,尽管这些变量之间的关系尚未完全确立。本研究的目的是在相关文献中搜索有关乳腺癌与职业风险因素暴露之间关联的信息。为此,使用以下关键词搜索电子数据库:乳腺癌和职业暴露。本综述纳入了2009年至2019年这10年间发表的40篇文章。接触镉等金属、化学产品、辐射和从事夜班工作的工人患乳腺癌的可能性更高。研究结果显示有重要证据支持乳腺癌与某些化学产品、电离辐射和夜班工作之间存在关联。然而,大多数研究难以确定这些变量之间的因果关系,这表明需要对这些问题进行进一步调查。

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本文引用的文献

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Postmenopausal breast cancer and occupational exposure to chemicals.绝经后乳腺癌与职业性接触化学物。
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Occupational variation in the risk of female breast cancer in the Nordic countries.北欧国家女性乳腺癌风险的职业差异。
Cancer Causes Control. 2018 Nov;29(11):1027-1038. doi: 10.1007/s10552-018-1076-2. Epub 2018 Aug 27.
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The relationship between night work and breast cancer.夜班工作与乳腺癌之间的关系。
Ann Occup Environ Med. 2018 Feb 6;30:11. doi: 10.1186/s40557-018-0221-4. eCollection 2018.

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