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Prolonged SARS-CoV-2 cell culture replication in respiratory samples from patients with severe COVID-19.严重 COVID-19 患者呼吸道样本中 SARS-CoV-2 的长时间细胞培养复制。
Clin Microbiol Infect. 2021 Jun;27(6):886-891. doi: 10.1016/j.cmi.2021.02.014. Epub 2021 Feb 22.
2
Emergence of a Highly Fit SARS-CoV-2 Variant.一种高度适应的严重急性呼吸综合征冠状病毒2变体的出现。
N Engl J Med. 2020 Dec 31;383(27):2684-2686. doi: 10.1056/NEJMcibr2032888. Epub 2020 Dec 16.
3
Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19.巴瑞替尼联合瑞德西韦治疗住院的新冠成年患者
N Engl J Med. 2021 Mar 4;384(9):795-807. doi: 10.1056/NEJMoa2031994. Epub 2020 Dec 11.
4
Repurposed Antiviral Drugs for Covid-19 - Interim WHO Solidarity Trial Results.用于治疗新冠肺炎的抗病毒药物 repurposed - 世界卫生组织团结试验中期结果
N Engl J Med. 2021 Feb 11;384(6):497-511. doi: 10.1056/NEJMoa2023184. Epub 2020 Dec 2.
5
COVID-19 severity in kidney transplant recipients is similar to nontransplant patients with similar comorbidities.肾移植受者 COVID-19 的严重程度与具有相似合并症的非移植患者相似。
Am J Transplant. 2021 Mar;21(3):1285-1294. doi: 10.1111/ajt.16416. Epub 2021 Jan 4.
6
Severe Acute Respiratory Syndrome Coronavirus 2 Clinical Syndromes and Predictors of Disease Severity in Hospitalized Children and Youth.严重急性呼吸综合征冠状病毒2型:住院儿童和青少年的临床综合征及疾病严重程度预测因素
J Pediatr. 2021 Mar;230:23-31.e10. doi: 10.1016/j.jpeds.2020.11.016. Epub 2020 Nov 14.
7
Assessment of Seroconversion to SARS-CoV-2 in a Cohort of Pediatric Kidney Transplant Recipients.一组小儿肾移植受者中 SARS-CoV-2 血清转化的评估
Front Pediatr. 2020 Oct 30;8:601327. doi: 10.3389/fped.2020.601327. eCollection 2020.
8
COVID-19 in Lung Transplant Recipients.肺移植受者中的 COVID-19 感染。
Transplantation. 2021 Jan 1;105(1):177-186. doi: 10.1097/TP.0000000000003508.
9
COVID-19 Therapeutics for Solid Organ Transplant Recipients; 6 Months Into the Pandemic: Where Are We Now?COVID-19 治疗药物在实体器官移植受者中的应用:大流行 6 个月后,我们现在在哪里?
Transplantation. 2021 Jan 1;105(1):56-60. doi: 10.1097/TP.0000000000003519.
10
Severe SARS-CoV-2 Infection in a Pediatric Patient Requiring Extracorporeal Membrane Oxygenation.一名需要体外膜肺氧合的儿科患者的严重新型冠状病毒2型感染
Case Rep Pediatr. 2020 Oct 9;2020:8885022. doi: 10.1155/2020/8885022. eCollection 2020.

严重急性呼吸综合征冠状病毒 2 型与儿科实体器官移植:已知和未知。

SARS-CoV-2 and pediatric solid organ transplantation: Current knowns and unknowns.

机构信息

Pediatric Infectious Diseases Unit, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland.

Cincinnati Children's Hospital, University of Cincinnati, Cincinnati, OH, USA.

出版信息

Pediatr Transplant. 2021 Aug;25(5):e13986. doi: 10.1111/petr.13986. Epub 2021 Mar 10.

DOI:10.1111/petr.13986
PMID:33689201
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8237081/
Abstract

The COVID-19 pandemic has proven to be a challenge in regard to the clinical presentation, prevention, diagnosis, and management of SARS-CoV-2 infection among children who are candidates for and recipients of SOT. By providing scenarios and frequently asked questions encountered in routine clinical practice, this document provides expert opinion and summarizes the available data regarding the prevention, diagnosis, and management of SARS-CoV-2 infection among pediatric SOT candidates and recipients and highlights ongoing knowledge gaps requiring further study. Currently available data are still lacking in the pediatric SOT population, but data have emerged in both the adult SOT and general pediatric population regarding the approach to COVID-19. The document provides expert opinion regarding prevention, diagnosis, and management of SARS-CoV-2 infection among pediatric SOT candidates and recipients.

摘要

COVID-19 大流行对儿童器官移植候选者和受者 SARS-CoV-2 感染的临床表现、预防、诊断和管理带来了挑战。本文件通过提供常规临床实践中遇到的场景和常见问题,提供了专家意见,并总结了有关儿科器官移植候选者和受者 SARS-CoV-2 感染预防、诊断和管理的现有数据,并强调了需要进一步研究的持续存在的知识空白。目前儿科器官移植人群的数据仍然缺乏,但在成人器官移植和一般儿科人群中已经出现了有关 COVID-19 处理方法的数据。本文件就儿科器官移植候选者和受者 SARS-CoV-2 感染的预防、诊断和管理提供了专家意见。