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评估九个非洲国家边境关闭对 COVID-19 发病率的影响:一项中断时间序列研究。

Evaluation of the effect of border closure on COVID-19 incidence rates across nine African countries: an interrupted time series study.

机构信息

Discipline of Public Health and Tropical Medicine, College of Public Health, Medical and Veterinary Sciences, James Cook University, Douglas, Townsville 4811, Australia.

Australian Institute of Tropical Health and Medicine, James Cook University, Douglas, Townsville 4811, Australia.

出版信息

Trans R Soc Trop Med Hyg. 2021 Oct 1;115(10):1174-1183. doi: 10.1093/trstmh/trab033.

Abstract

BACKGROUND

Border closure is one of the policy changes implemented to mitigate against coronavirus disease 2019 (COVID-19). We evaluated the effect of border closure on the incidence rate of COVID-19 across nine African countries.

METHODS

An interrupted time series analysis was used to assess COVID-19 incidence rates in Egypt, Tunisia, Democratic Republic of the Congo (DRC), Ethiopia, Kenya, Ghana, Nigeria, Senegal and South Africa (SA). Data were collected between 14 February and 19 July 2020 from online data repositories. The linear trend and magnitude of change were evaluated using the itsa function with ordinary least-squares regression in Stata with a 7-d deferred interruption point, which allows a period of diffusion post-border closure.

RESULTS

Overall, the countries recorded an increase in the incidence rate of COVID-19 after border closure. However, when compared with matched control groups, SA, Nigeria, Ghana, Egypt and Kenya showed a higher incidence rate trend. In contrast, Ethiopia, DRC and Tunisia showed a lower trend compared with their controls.

CONCLUSIONS

The implementation of border closures within African countries had minimal effect on the incidence of COVID-19. The inclusion of other control measures such as enhanced testing capacity and improved surveillance activities will reveal the effectiveness of border closure measures.

摘要

背景

边境关闭是为减轻 2019 年冠状病毒病(COVID-19)而实施的政策变化之一。我们评估了边境关闭对九个非洲国家 COVID-19 发病率的影响。

方法

采用中断时间序列分析评估埃及、突尼斯、刚果民主共和国(DRC)、埃塞俄比亚、肯尼亚、加纳、尼日利亚、塞内加尔和南非(SA)的 COVID-19 发病率。数据于 2020 年 2 月 14 日至 7 月 19 日从在线数据存储库中收集。使用 Stata 中的 itsa 函数和普通最小二乘法回归评估线性趋势和变化幅度,具有 7 天的延迟中断点,允许在边境关闭后有一段扩散期。

结果

总体而言,这些国家在边境关闭后 COVID-19 的发病率呈上升趋势。然而,与匹配的对照组相比,南非、尼日利亚、加纳、埃及和肯尼亚的发病率趋势更高。相比之下,埃塞俄比亚、刚果民主共和国和突尼斯的发病率趋势较低。

结论

非洲国家实施边境关闭对 COVID-19 的发病率影响不大。纳入其他控制措施,如增强检测能力和改善监测活动,将揭示边境关闭措施的有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c1b/8486738/7a104f099245/trab033fig1.jpg

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