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American Society of Hematology 2020 guidelines for sickle cell disease: management of acute and chronic pain.美国血液学会2020年镰状细胞病指南:急性和慢性疼痛的管理
Blood Adv. 2020 Jun 23;4(12):2656-2701. doi: 10.1182/bloodadvances.2020001851.
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Association of Hospital Discharge Against Medical Advice With Readmission and In-Hospital Mortality.医院出院劝阻与再入院和住院死亡率的关联。
JAMA Netw Open. 2020 Jun 1;3(6):e206009. doi: 10.1001/jamanetworkopen.2020.6009.
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Perceptions of US Adolescents and Adults With Sickle Cell Disease on Their Quality of Care.美国镰状细胞病青少年和成年患者对其护理质量的认知。
JAMA Netw Open. 2020 May 1;3(5):e206016. doi: 10.1001/jamanetworkopen.2020.6016.
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Epidemiology and Predictors of all-cause 30-Day readmission in patients with sickle cell crisis.镰状细胞危象患者全因 30 天再入院的流行病学和预测因素。
Sci Rep. 2020 Feb 7;10(1):2082. doi: 10.1038/s41598-020-58934-3.
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Ketamine and lidocaine infusions decrease opioid consumption during vaso-occlusive crisis in adolescents with sickle cell disease.氯胺酮和利多卡因输注可减少镰状细胞病青少年血管闭塞性危象期间的阿片类药物用量。
Curr Opin Support Palliat Care. 2019 Dec;13(4):402-407. doi: 10.1097/SPC.0000000000000437.
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Chronic pain in adults with sickle cell disease is associated with alterations in functional connectivity of the brain.成人镰状细胞病的慢性疼痛与大脑功能连接的改变有关。
PLoS One. 2019 May 20;14(5):e0216994. doi: 10.1371/journal.pone.0216994. eCollection 2019.
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The REDCap consortium: Building an international community of software platform partners.REDCap 联盟:构建软件平台合作伙伴的国际社区。
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8
Improving Care for Sickle Cell Pain Crisis Using a Multidisciplinary Approach.采用多学科方法改善镰状细胞疼痛危象的护理。
Pediatrics. 2019 May;143(5). doi: 10.1542/peds.2018-2218. Epub 2019 Apr 3.
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AAAPT Diagnostic Criteria for Acute Sickle Cell Disease Pain.AAAPT 急性镰状细胞病疼痛诊断标准。
J Pain. 2019 Jul;20(7):746-759. doi: 10.1016/j.jpain.2018.12.003. Epub 2018 Dec 19.
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Risk factors for hospitalizations and readmissions among individuals with sickle cell disease: results of a U.S. survey study.镰状细胞病患者住院和再入院的风险因素:一项美国调查研究的结果
Hematology. 2019 Dec;24(1):189-198. doi: 10.1080/16078454.2018.1549801.

实施个体化疼痛护理计划可降低高利用镰状细胞病成年患者的住院时间和住院率。

Implementation of Individualized Pain Care Plans Decreases Length of Stay and Hospital Admission Rates for High Utilizing Adults with Sickle Cell Disease.

机构信息

Department of Anesthesiology, Section of Pain Medicine, Wake Forest School of Medicine, North Carolina, USA.

Department of Emergency Medicine, Wake Forest School of Medicine, North Carolina, USA.

出版信息

Pain Med. 2021 Aug 6;22(8):1743-1752. doi: 10.1093/pm/pnab092.

DOI:10.1093/pm/pnab092
PMID:33690845
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8346918/
Abstract

OBJECTIVE

Patients with sickle cell disease (SCD) face inconsistent effective analgesic management, leading to high inpatient healthcare utilization and significant financial burden for healthcare institutions. Current evidence does not provide guidance for inpatient management of acute pain in adults with sickle cell disease. We conducted a retrospective analysis of a longitudinal cohort quality improvement project to characterize the role of individualized care plans on improving patient care and reducing financial burden in high healthcare-utilizing patients with SCD-related pain.

METHODS

Individualized care plans were developed for patients with hospital admissions resulting from pain associated with sickle cell disease. A 2-year prospective longitudinal cohort quality improvement project was performed and retrospectively analyzed. Primary outcome measure was duration of hospitalization. Secondary outcome measures included: pain intensity; 7, 30, and 90-day readmission rates; cost per day; total admissions; total cost per year; analgesic regimen at index admission; and discharge disposition.

RESULTS

Duration of hospitalization, the primary outcome, significantly decreased by 1.23 days with no worsening of pain intensity scores. Seven-day readmission decreased by 34%. Use of intravenous hydromorphone significantly decreased by 25%. The potential cost saving was $1,398,827 as a result of this quality initiative.

CONCLUSIONS

Implementation of individualized care plans reduced both admission rate and financial burden of high utilizing patients. Importantly, pain outcomes were not diminished. Results suggest that individualized care plans are a promising strategy for managing acute pain crisis in adult sickle cell patients from both care-focused and utilization outcomes.

摘要

目的

镰状细胞病(SCD)患者的有效镇痛管理存在不一致的情况,导致住院医疗利用率高,医疗机构负担沉重。目前的证据并未为成人 SCD 相关疼痛的住院管理提供指导。我们对一项纵向队列质量改进项目进行了回顾性分析,以确定个体化护理计划在改善患者护理和减轻高医疗利用率 SCD 相关疼痛患者的经济负担方面的作用。

方法

为因镰状细胞病相关疼痛住院的患者制定个体化护理计划。进行了为期 2 年的前瞻性纵向队列质量改进项目,并进行了回顾性分析。主要结局指标为住院时间。次要结局指标包括:疼痛强度;7、30 和 90 天的再入院率;每天的费用;总入院次数;每年的总费用;指数入院时的镇痛方案;以及出院处置。

结果

住院时间(主要结局)显著缩短了 1.23 天,而疼痛强度评分无恶化。7 天再入院率降低了 34%。静脉注射氢吗啡酮的使用率显著降低了 25%。由于这项质量改进措施,潜在的节省成本为 1398827 美元。

结论

实施个体化护理计划降低了高利用率患者的入院率和经济负担。重要的是,疼痛结局并未恶化。结果表明,个体化护理计划是管理成人镰状细胞病患者急性疼痛危机的一种有前途的策略,从护理重点和利用结果两方面来看都是如此。