Department of Periodontics, University of Washington, Seattle, Washington, USA.
Oral Biology Research Unit, Faculty of Dentistry, Khon Kaen University, Khon Kaen, Thailand.
Periodontol 2000. 2021 Jun;86(1):188-200. doi: 10.1111/prd.12369. Epub 2021 Mar 10.
Years of coevolution with resident microbes has made them an essential component of health. Yet, little is known about oral commensal bacteria's contribution to and role in the maintenance of oral health and homeostasis. Commensal bacteria are speculated to play a host protective role in the maintenance of health. In this review, we describe and provide examples of the coordinate regulation that occurs between oral commensal bacteria and the host innate immune response to modulate and maintain oral homeostasis.
与常驻微生物的多年共同进化使它们成为健康的重要组成部分。然而,对于口腔共生菌在维持口腔健康和体内平衡中的作用和贡献知之甚少。推测共生菌在维持健康方面发挥着宿主保护作用。在这篇综述中,我们描述并举例说明了口腔共生菌与宿主固有免疫反应之间发生的协调调节,以调节和维持口腔内的平衡。