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改良的最小接触 COVID-19 工作流程可实现非危重症患者的安全、远程肠外营养处方。

Modified minimal-contact COVID-19 workflow allows for safe, remote parenteral nutrition prescribing in non-critically ill patients.

机构信息

Department of Gastroenterology and Hepatology, Singapore General Hospital, Singapore.

Department of Pharmacy, Singapore General Hospital, Singapore.

出版信息

JPEN J Parenter Enteral Nutr. 2021 Aug;45(6):1364-1368. doi: 10.1002/jpen.2104. Epub 2021 Apr 20.

DOI:10.1002/jpen.2104
PMID:33694246
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8236975/
Abstract

BACKGROUND

In line with recent guidance from the American Society for Parenteral and Enteral Nutrition (ASPEN) and the European Society for Clinical Nutrition and Metabolism (ESPEN) to minimize healthcare team exposure by clustering care and relying on other providers or telehealth to collect relevant nutrition assessments, our nutrition support team has adopted a modified workflow using information technology to provide parenteral nutrition (PN) remotely in a safe and timely manner. We aim to compare our prescribing adequacy and PN-related complications before and during the coronavirus disease 2019 (COVID-19) outbreak using the modified workflow in non-critically ill patients.

METHODS

This study reviewed a prospectively recruited cohort of adults receiving PN in the general wards or high-dependency units from December 5, 2019, to April 15, 2020. Demographic data, nutrition assessment, PN prescriptions, blood results, electronic notes, capillary blood glucose monitoring, and catheter-related bloodstream infection rates were reviewed for patients who received PN.

RESULTS

We found that patients who started PN during COVID-19 were more malnourished with lower body mass index and higher proportion of Subjective Global Assessment B/C scores (52 [92.9%] vs 36 [73.5%], P < .005). The proportion of patients who achieved target energy amounts within 5 days was similar in both groups. Protein prescription was >1 g/kg/day in both groups, though there was a trend of higher protein prescription during COVID-19. Complications were similar in both groups.

CONCLUSION

Our study demonstrates that minimal contact with effective multidisciplinary communication using the modified workflow can allow for safe and timely PN administration.

摘要

背景

为了遵循美国肠外肠内营养学会(ASPEN)和欧洲临床营养和代谢学会(ESPEN)的最新指南,通过集中护理并依靠其他提供者或远程医疗来收集相关营养评估,以尽量减少医疗团队的暴露,我们的营养支持团队采用了一种经过修改的工作流程,使用信息技术远程提供肠外营养(PN),以安全、及时的方式提供肠外营养。我们旨在比较使用修改后的工作流程在非危重病患者中 COVID-19 爆发前后的处方充足性和 PN 相关并发症。

方法

本研究回顾性招募了 2019 年 12 月 5 日至 2020 年 4 月 15 日期间在普通病房或高依赖病房接受 PN 的成人患者。对接受 PN 的患者进行了人口统计学数据、营养评估、PN 处方、血液结果、电子病历、毛细血管血糖监测和导管相关血流感染率的回顾性分析。

结果

我们发现 COVID-19 期间开始接受 PN 的患者营养状况更差,体重指数更低,主观整体评估 B/C 评分的比例更高(52[92.9%] vs 36[73.5%],P<.005)。两组患者在 5 天内达到目标能量量的比例相似。两组患者的蛋白质处方均>1g/kg/天,尽管 COVID-19 期间的蛋白质处方呈上升趋势。两组并发症相似。

结论

我们的研究表明,使用经过修改的工作流程进行最小接触和有效的多学科沟通,可以安全、及时地进行 PN 管理。

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本文引用的文献

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ESPEN expert statements and practical guidance for nutritional management of individuals with SARS-CoV-2 infection.ESPEN 专家声明和关于 SARS-CoV-2 感染个体营养管理的实用指南。
Clin Nutr. 2020 Jun;39(6):1631-1638. doi: 10.1016/j.clnu.2020.03.022. Epub 2020 Mar 31.
2
Management of acute intestinal failure: A position paper from the European Society for Clinical Nutrition and Metabolism (ESPEN) Special Interest Group.急性肠衰竭的管理:欧洲临床营养与代谢学会(ESPEN)特别兴趣小组的立场文件。
Clin Nutr. 2016 Dec;35(6):1209-1218. doi: 10.1016/j.clnu.2016.04.009. Epub 2016 Apr 19.